- A function for Rac1 in the terminal differentiation and pigmentation of hair
[作者:Behrendt, K; Klatte, J; Pofahl, R; Bloch, W; Smyth, N; Tscharntke, M; Krieg, T; Paus, R; Niessen, C; Niemann, C; Brakebusch, C; Haase, I,期刊:Journal of cell science, 页码:896-905 , 文章类型: Article,,卷期:2012年125-4]
- The small GTPase Rac1 is ubiquitously expressed in proliferating and differentiating layers of the epidermis and hair follicles. Previously, Rac1 was shown to regulate stem cell behaviour in these compartments. We have a...
- In vivo fluorescence resonance energy transfer imaging reveals differential activation of Rho-family GTPases in glioblastoma cell invasion
[作者:Hirata, E; Yukinaga, H; Kamioka, Y; Arakawa, Y; Miyamoto, S; Okada, T; Sahai, E; Matsuda, M,期刊:Journal of cell science, 页码:858-868 , 文章类型: Article,,卷期:2012年125-4]
- Two-photon excitation microscopy was used to visualized two different modes of invasion at perivascular and intraparenchymal regions of rat C6 glioblastoma cells that were orthotopically implanted into rat brains. Probes...
- A motif of eleven amino acids is a structural adaptation that facilitates motor capability of eutherian prestin
[作者:Tan, XD; Pecka, JL; Tang, J; Lovas, S; Beisel, KW; He, DZZ,期刊:Journal of cell science, 页码:1039-1047 , 文章类型: Article,,卷期:2012年125-4]
- Cochlear outer hair cells (OHCs) alter their length in response to transmembrane voltage changes. This so-called electromotility is the result of conformational changes of membrane-bound prestin. Prestin-based OHC motili...
- A short Gfi-1B isoform controls erythroid differentiation by recruiting the LSD1-CoREST complex through the dimethylation of its SNAG domain
[作者:Laurent, B; Randrianarison-Huetz, V; Frisan, E; Andrieu-Soler, C; Soler, E; Fontenay, M; Dusanter-Fourt, I; Dumenil, D,期刊:Journal of cell science, 页码:993-1002 , 文章类型: Article,,卷期:2012年125-4]
- Gfi-1B is a transcriptional repressor essential for the regulation of erythropoiesis and megakaryopoiesis. Here we identify Gfi-1B p32, a Gfi-1B isoform, as essential for erythroid differentiation. Gfi-1B p32 is generate...
- Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu
[作者:Ayling, LJ; Briddon, SJ; Halls, ML; Hammond, GRV; Vaca, L; Pacheco, J; Hill, SJ; Cooper, DMF,期刊:Journal of cell science, 页码:869-886 , 文章类型: Article,,卷期:2012年125-4]
- The central and pervasive influence of cAMP on cellular functions underscores the value of stringent control of the organization of adenylyl cyclases (ACs) in the plasma membrane. Biochemical data suggest that ACs reside...
- Kinetochores accelerate centrosome separation to ensure faithful chromosome segregation
[作者:Mchedlishvili, N; Wieser, S; Holtackers, R; Mouysset, J; Belwal, M; Amaro, AC; Meraldi, P,期刊:Journal of cell science, 页码:906-918 , 文章类型: Article,,卷期:2012年125-4]
- At the onset of mitosis, cells need to break down their nuclear envelope, form a bipolar spindle and attach the chromosomes to microtubules via kinetochores. Previous studies have shown that spindle bipolarization can oc...
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