- Rigid Core and Flexible Terminus STRUCTURE OF SOLUBILIZED LIGHT-HARVESTING CHLOROPHYLL a/b COMPLEX (LHCII) MEASURED BY EPR
[作者:Dockter, C; Muller, AH; Dietz, C; Volkov, A; Polyhach, Y; Jeschke, G; Paulsen, H,期刊:Journal of Biological Chemistry, 页码:2915-2925 , 文章类型: Article,,卷期:2012年287-4]
- The structure of the major light-harvesting chlorophyll a/b complex ( LHCII) was analyzed by pulsed EPR measurements and compared with the crystal structure. Site-specific spin labeling of the recombinant protein allowed...
- A Novel Role for alpha-Tocopherol Transfer Protein (alpha-TTP) in Protecting against Chloroquine Toxicity
[作者:Shichiri, M; Kono, N; Shimanaka, Y; Tanito, M; Rotzoll, DE; Yoshida, Y; Hagihara, Y; Tamai, H; Arai, H,期刊:Journal of Biological Chemistry, 页码:2926-2934 , 文章类型: Article,,卷期:2012年287-4]
- Chloroquine (CQ) is a widely prescribed anti-malarial agent and is also prescribed to treat autoimmune diseases. Clinical treatment with CQ is often accompanied by serious side effects such as hepatitis and retinopathy. ...
- Characterization of Heparin-induced Glyceraldehyde-3-phosphate Dehydrogenase Early Amyloid-like Oligomers and Their Implication in alpha-Synuclein Aggregation
[作者:Torres-Bugeau, CM; Avila, CL; Raisman-Vozari, R; Papy-Garcia, D; Itri, R; Barbosa, LRS; Cortez, LM; Sim, VL; Chehin, RN,期刊:Journal of Biological Chemistry, 页码:2398-2409 , 文章类型: Article,,卷期:2012年287-4]
- Lewy bodies and Lewy neurites, neuropathological hallmarks of several neurological diseases, are mainly made of filamentous assemblies of alpha-synuclein. However, other macromolecules including Tau, ubiquitin, glycerald...
- Critical Role for Heat Shock Protein 20 (HSP20) in Migration of Malarial Sporozoites
[作者:Montagna, GN; Buscaglia, CA; Munter, S; Goosmann, C; Frischknecht, F; Brinkmann, V; Matuschewski, K,期刊:Journal of Biological Chemistry, 页码:2410-2422 , 文章类型: Article,,卷期:2012年287-4]
- Plasmodium sporozoites, single cell eukaryotic pathogens, use their own actin/myosin-based motor machinery for life cycle progression, which includes forward locomotion, penetration of cellular barriers, and invasion of ...
- Amyloid Precursor Protein Revisited NEURON-SPECIFIC EXPRESSION AND HIGHLY STABLE NATURE OF SOLUBLE DERIVATIVES
[作者:Guo, QX; Li, HM; Gaddam, SSK; Justice, NJ; Robertson, CS; Zheng, H,期刊:Journal of Biological Chemistry, 页码:2437-2445 , 文章类型: Article,,卷期:2012年287-4]
- APP processing and amyloid-beta production play a central role in Alzheimer disease pathogenesis. APP has been considered a ubiquitously expressed protein. In addition to amyloid-beta, alpha- or beta-secretase-dependent ...
- Macromolecular Crowding Regulates Assembly of mRNA Stress Granules after Osmotic Stress NEW ROLE FOR COMPATIBLE OSMOLYTES
[作者:Bounedjah, O; Hamon, L; Savarin, P; Desforges, B; Curmi, PA; Pastre, D,期刊:Journal of Biological Chemistry, 页码:2446-2458 , 文章类型: Article,,卷期:2012年287-4]
- The massive uptake of compatible osmolytes such as betaine, taurine, and myo-inositol is a protective response shared by all eukaryotes exposed to hypertonic stress. Their accumulation results mostly from the expression ...
- Interleukin-19 (IL-19) Induces Heme Oxygenase-1 (HO-1) Expression and Decreases Reactive Oxygen Species in Human Vascular Smooth Muscle Cells
[作者:Gabunia, K; Ellison, SP; Singh, H; Datta, P; Kelemen, SE; Rizzo, V; Autieri, MV,期刊:Journal of Biological Chemistry, 页码:2477-2484 , 文章类型: Article,,卷期:2012年287-4]
- Heme oxygenase-1 (HO-1) has potent anti-inflammatory activity and recognized vascular protective effects. We have recently described the expression and vascular protective effects of an anti-inflammatory interleukin (IL-...
- Core Fucosylation of mu Heavy Chains Regulates Assembly and Intracellular Signaling of Precursor B Cell Receptors
[作者:Li, WZ; Liu, QP; Pang, Y; Jin, JH; Wang, HG; Cao, HY; Li, Z; Wang, X; Ma, B; Chi, Y; Wang, RJ; Kondo, A; Gu, JG; Taniguchi, N,期刊:Journal of Biological Chemistry, 页码:2500-2508 , 文章类型: Article,,卷期:2012年287-4]
- alpha 1,6-Fucosyltransferase (Fut8) knock-out (Fut8(-/-)) mice showed an abnormality in pre-B cell generation. Membrane assembly of pre-BCR is a crucial checkpoint for pre-B cell differentiation and proliferation in both...
- p53-dependent Induction of PVT1 and miR-1204
[作者:Barsotti, AM; Beckerman, R; Laptenko, O; Huppi, K; Caplen, NJ; Prives, C,期刊:Journal of Biological Chemistry, 页码:2509-2519 , 文章类型: Article,,卷期:2012年287-4]
- p53 is a tumor suppressor protein that acts as a transcription factor to regulate (either positively or negatively) a plethora of downstream target genes. Although its ability to induce protein coding genes is well docum...
- Dbf4 Is Direct Downstream Target of Ataxia Telangiectasia Mutated (ATM) and Ataxia Telangiectasia and Rad3-related (ATR) Protein to Regulate Intra-S-phase Checkpoint
[作者:Lee, AYL; Chiba, T; Truong, LN; Cheng, AN; Do, J; Cho, MJ; Chen, LC; Wu, XH,期刊:Journal of Biological Chemistry, 页码:2531-2543 , 文章类型: Article,,卷期:2012年287-4]
- Dbf4/Cdc7 (Dbf4-dependent kinase (DDK)) is activated at the onset of S-phase, and its kinase activity is required for DNA replication initiation from each origin. We showed that DDK is an important target for the S-phase...
- The C Terminus of Bax Inhibitor-1 Forms a Ca2+-permeable Channel Pore
[作者:Bultynck, G; Kiviluoto, S; Henke, N; Ivanova, H; Schneider, L; Rybalchenko, V; Luyten, T; Nuyts, K; De Borggraeve, W; Bezprozvanny, I; Parys, JB; De Smedt, H; Missiaen, L; Methner, A,期刊:Journal of Biological Chemistry, 页码:2544-2557 , 文章类型: Article,,卷期:2012年287-4]
- Bax inhibitor-1 (BI-1) is a multitransmembrane domain-spanning endoplasmic reticulum (ER)-located protein that is evolutionarily conserved and protects against apoptosis and ER stress. Furthermore, BI-1 is proposed to mo...
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