- Inecalcitol, an analog of 1a,25(OH)2D3, induces growth arrest of androgen-dependent prostate cancer cells
[作者:Okamoto, R; Delansorne, R; Wakimoto, N; Doan, NB; Akagi, T; Shen, M; Ho, QH; Said, JW; Koeffler, HP,期刊:International Journal of Cancer, 页码:2464-2473 , 文章类型: Article,,卷期:2012年130-10]
- 19-nor-14-epi-23-yne-1,25(OH)2D3 (inecalcitol) is a unique vitamin D3 analog. We evaluated the activity of inecalcitol in a human prostate cancer model system. The analog was 11-fold more potent than 1,25(OH)2D3 in causi...
- Active-specific immunotherapy of human cancers with the heat shock protein Gp96urevisited
[作者:Randazzo, M; Terness, P; Opelz, G; Kleist, C,期刊:International Journal of Cancer, 页码:2219-2231 , 文章类型: Review,,卷期:2012年130-10]
- The passive administration of specific antibodies that selectively target tumors is a well-known strategy in cancer treatment. Active immunotherapy using peptide vaccines, in contrast, is expected to induce specific, cyt...
- Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis
[作者:Lax, S; Schauer, G; Prein, K; Kapitan, M; Silbert, D; Berghold, A; Berger, A; Trauner, M,期刊:International Journal of Cancer, 页码:2232-2239 , 文章类型: Article,,卷期:2012年130-10]
- The nuclear bile acid receptor/farnesoid X receptor (FXR; NR1H4) is involved in bile acid homeostasis, cell proliferation and apoptosis and has been linked to intestinal carcinogenesis in mice. Aim of this study was to a...
- ARFGAP3, an androgen target gene, promotes prostate cancer cell proliferation and migration
[作者:Obinata, D; Takayama, K; Urano, T; Murata, T; Ikeda, K; Horie-Inoue, K; Ouchi, Y; Takahashi, S; Inoue, S,期刊:International Journal of Cancer, 页码:2240-2248 , 文章类型: Article,,卷期:2012年130-10]
- ADP ribosylation factor GTPase-activating protein 3 (ARFGAP3) is a GTPase-activating protein that associates with the Golgi apparatus and regulates the vesicular trafficking pathway. In the present study, we examined the...
- Deregulation of Snai2 is associated with metastasis and poor prognosis in tongue squamous cell carcinoma
[作者:Wang, C; Liu, XQ; Huang, HZ; Ma, HB; Cai, WX; Hou, JS; Huang, L; Dai, Y; Yu, TW; Zhou, XF,期刊:International Journal of Cancer, 页码:2249-2258 , 文章类型: Article,,卷期:2012年130-10]
- The members of the Snail superfamily of zinc-finger transcription factors, including Snai1 and Snai2, are involved in essential biological processes, such as epithelialmesenchymal transition (EMT). Although Snai1 has bee...
- Reactivation of p53 mutants by p53 reactivation and induction of massive apoptosis in thyroid cancer cells
[作者:Messina, RL; Sanfilippo, M; Vella, V; Pandini, G; Vigneri, P; Nicolosi, ML; Giani, F; Vigneri, R; Frasca, F,期刊:International Journal of Cancer, 页码:2259-2270 , 文章类型: Article,,卷期:2012年130-10]
- Most undifferentiated thyroid carcinomas express p53 mutants and thereafter, are very resistant to chemotherapy. p53 reactivation and induction of massive apoptosis (Prima-1) is a compound restoring the tumor-suppressor ...
- Versican V1 isoform regulates cell-associated matrix formation and cell behavior differentially from aggrecan in Swarm rat chondrosarcoma cells
[作者:Wasa, J; Nishida, Y; Shinomura, T; Isogai, Z; Futamura, N; Urakawa, H; Arai, E; Kozawa, E; Tsukushi, S; Ishiguro, N,期刊:International Journal of Cancer, 页码:2271-2281 , 文章类型: Article,,卷期:2012年130-10]
- Versican, a large chondroitin sulfate proteoglycan that binds hyaluronan and is composed of large extracellular matrix aggregates, has been shown to correlate with tumor progression. No studies have examined the roles of...
- B7-H3 contributes to the metastatic capacity of melanoma cells by modulation of known metastasis-associated genes
[作者:Tekle, C; Nygren, MK; Chen, YW; Dybsjord, I; Nesland, JM; Maelandsmo, GM; Fodstad, O,期刊:International Journal of Cancer, 页码:2282-2290 , 文章类型: Article,,卷期:2012年130-10]
- B7-H3, an immunoregulatory protein, is known to play a role in tumor progression. In many cancer types, observed correlations between high B7-H3 expression and poor prognosis have been attributed to involvement in antitu...
- Novel senescence associated gene, YPEL3, is repressed by estrogen in ER plus mammary tumor cells and required for tamoxifen-induced cellular senescence
[作者:Tuttle, R; Miller, KR; Maiorano, JN; Termuhlen, PM; Gao, YP; Berberich, SJ,期刊:International Journal of Cancer, 页码:2291-2299 , 文章类型: Article,,卷期:2012年130-10]
- Estrogen signaling plays an important role in breast carcinogenesis. An increased understanding of estrogen gene targets and their effects will allow for more directed and effective therapies for individuals with breast ...
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