- Autoimmunity, Intestinal Lymphoid Hyperplasia, and Defects in Mucosal B-Cell Homeostasis in Patients With PTEN Hamartoma Tumor Syndrome
[作者:Heindl, M; Handel, N; Ngeow, J; Kionke, J; Wittekind, C; Kamprad, M; Rensing-Ehl, A; Ehl, S; Reifenberger, J; Loddenkemper, C; Maul, J; Hoffmeister, A; Aretz, S; Kiess, W; Eng, C; Uhlig, HH,期刊:Gastroenterology, 页码:1093-+ , 文章类型: Article,,卷期:2012年142-5]
- The Phosphatase And Tensin Homolog Deleted On Chromosome 10 (PTEN) regulates the phosphoinositol-3-kinase (PI3K)-AKT signaling pathway. In a series of 34 patients with PTEN mutations, we described gastrointestinal lympho...
- Abnormal Activation of Autophagy-Induced Crinophagy in Paneth Cells From Patients With Crohn's Disease
[作者:Thachil, E; Hugot, JP; Arbeille, B; Paris, R; Grodet, A; Peuchmaur, M; Codogno, P; Barreau, F; Ogier-Denis, E; Berrebi, D; Viala, J,期刊:Gastroenterology, 页码:1097-+ , 文章类型: Article,,卷期:2012年142-5]
- Autophagy-related 16 like-1 (ATG16L-1), immunity-related GTPase-M (IRGM), and nucleotide-binding oligomerization domain-containing 2 (NOD2) regulate autophagy, and variants in these genes have been associated with predis...
- Adalimumab Induces and Maintains Mucosal Healing in Patients With Crohn's Disease: Data From the EXTEND Trial
[作者:Rutgeerts, P; Van Assche, G; Sandborn, WJ; Wolf, DC; Geboes, K; Colombel, JF; Reinisch, W; Kumar, A; Lazar, A; Camez, A; Lomax, KG; Pollack, PF; D'Haens, G,期刊:Gastroenterology, 页码:1102-+ , 文章类型: Article,,卷期:2012年142-5]
- BACKGROUND & AIMS: We investigated the efficacy of adalimumab for inducing and maintaining mucosal healing in patients with Crohn's disease (CD). METHODS: A randomized, double-blind, placebo-controlled trial (extend the ...
- Comparison of Methods to Detect Neoplasia in Patients Undergoing Endoscopic Ultrasound-Guided Fine-Needle Aspiration
[作者:Levy, MJ; Oberg, TN; Campion, MB; Clayton, AC; Halling, KC; Henry, MR; Kipp, BR; Sebo, TJ; Zhang, J; Enders, FT; Clain, JE; Gleeson, FC; Rajan, E; Roberts, LR; Topazian, MD; Wang, KK; Gores, GJ,期刊:Gastroenterology, 页码:1112-+ , 文章类型: Article,,卷期:2012年142-5]
- BACKGROUND & AIMS: Digital image analysis (DIA) and fluorescence in situ hybridization (FISH) can be used to evaluate biliary strictures with greater accuracy than conventional cytology (CC). We performed a prospective e...
- Hepatic Cell-Type Specific Gene Expression Better Predicts HCV Treatment Outcome Than IL28B Genotype
[作者:McGilvray, I; Feld, JJ; Chen, LM; Pattullo, V; Guindi, M; Fischer, S; Borozan, I; Xie, G; Selzner, N; Heathcote, EJ; Siminovitch, K,期刊:Gastroenterology, 页码:1122-+ , 文章类型: Article,,卷期:2012年142-5]
- BACKGROUND & AIMS: Cell-type specific expression patterns of hepatic interferon-stimulated genes (ISGs) and single nucleotide polymorphisms (SNPs) near the IL28B gene are associated with response to interferon-based ther...
- Risk for Immune-Mediated Graft Dysfunction in Liver Transplant Recipients With Recurrent HCV Infection Treated With Pegylated Interferon
[作者:Levitsky, J; Fiel, MI; Norvell, JP; Wang, E; Watt, KD; Curry, MP; Tewani, S; McCashland, TM; Hoteit, MA; Shaked, A; Saab, S; Chi, AC; Tien, A; Schiano, TD,期刊:Gastroenterology, 页码:1132-+ , 文章类型: Article,,卷期:2012年142-5]
- BACKGROUND & AIMS: Patients with recurrent hepatitis C virus infection treated with pegylated interferon (PEG) after liver transplantation can develop severe immune-mediated graft dysfunction (IGD) characterized by plasm...
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