- Rising Incidence of Type 1 Diabetes Is Associated With Altered Immunophenotype at Diagnosis
[作者:Long, AE; Gillespie, KM; Rokni, S; Birtgley, PJ; Williams, AJK,期刊:Diabetes, 页码:683-686 , 文章类型: Article,,卷期:2012年61-3]
- The incidence of type 1 diabetes has increased rapidly over recent decades, particularly in young children. We aimed to determine whether this rise was associated with changes in patterns of humoral islet autoimmunity at...
- Type 1 Diabetes Is Associated With Enterovirus Infection in Gut Mucosa
[作者:Oikarinen, M; Tauriainen, S; Oikarinen, S; Honkanen, T; Collin, P; Rantala, I; Maki, M; Kaukinen, K; Hyoty, H,期刊:Diabetes, 页码:687-691 , 文章类型: Article,,卷期:2012年61-3]
- Enterovirus infections have been linked to type 1 diabetes in several studies. Enteroviruses also have tropism to pancreatic islets and can cause beta-cell damage in experimental models. Viral persistence has been suspec...
- Age-Related Impairment in Insulin Release The Essential Role of beta(2)-Adrenergic Receptor
[作者:Santulli, G; Lombardi, A; Sorriento, D; Anastasio, A; Del Giudice, C; Formisano, P; Beguinot, F; Trimarco, B; Miele, C; Iaccarino, G,期刊:Diabetes, 页码:692-701 , 文章类型: Article,,卷期:2012年61-3]
- In this study, we investigated the significance of beta(2)-adrenergic receptor (beta(2)AR) in age-related impaired insulin secretion and glucose homeostasis. We characterized the metabolic phenotype of beta(2)AR-null C57...
- Interbirth Interval Is Associated With Childhood Type 1 Diabetes Risk
[作者:Cardwell, CR; Svensson, J; Waldhoer, T; Ludvigsson, J; Sadauskaite-Kuehne, V; Roberts, CL; Parslow, RC; Wadsworth, EJK; Brigis, G; Urbonaite, B; Schober, E; Devoti, G; Ionescu-Tirgoviste, C; de Beaufort, CE; Soltesz, G; Patterson, CC,期刊:Diabetes, 页码:702-707 , 文章类型: Article,,卷期:2012年61-3]
- Short interbirth interval has been associated with maternal complications and childhood autism and leukemia, possibly due to deficiencies in maternal micronutrients at conception or increased exposure to sibling infectio...
- Glycemic Control and Cardiovascular Mortality in Hemodialysis Patients With Diabetes A 6-Year Cohort Study
[作者:Ricks, J; Molnar, MZ; Kovesdy, CP; Shah, A; Nissenson, AR; Williams, M; Kalantar-Zadeh, K,期刊:Diabetes, 页码:708-715 , 文章类型: Article,,卷期:2012年61-3]
- Previous observational studies using differing methodologies have yielded inconsistent results regarding the association between glycemic control and outcomes in diabetic patients receiving maintenance hemodialysis (MHD)...
- Cannabinoid 1 Receptor Promotes Cardiac Dysfunction, Oxidative Stress, Inflammation, and Fibrosis in Diabetic Cardiomyopathy
[作者:Rajesh, M; Batkai, S; Kechrid, M; Mukhopadhyay, P; Lee, WS; Horvath, B; Holovac, E; Cinar, R; Liaudet, L; Mackie, K; Hasko, G; Pacher, P,期刊:Diabetes, 页码:716-727 , 文章类型: Article,,卷期:2012年61-3]
- Endocannabinoids and cannabinoid 1 (CB1) receptors have been implicated in cardiac dysfunction, inflammation, and cell death associated with various forms of shock, heart failure, and atherosclerosis, in addition to thei...
- Catalase Deficiency Accelerates Diabetic Renal Injury Through Peroxisomal Dysfunction
[作者:Hwang, I; Lee, J; Huh, JY; Park, J; Lee, HB; Ho, YS; Ha, H,期刊:Diabetes, 页码:728-738 , 文章类型: Article,,卷期:2012年61-3]
- Mitochondrial reactive oxygen species (ROS) play an important role in diabetes complications, including diabetic nephropathy (DN). Plasma free fatty acids (FFAs) as well as glucose are increased in diabetes, and peroxiso...
- Gene Expression Differences in Skin Fibroblasts in Identical Twins Discordant for Type 1 Diabetes
[作者:Caramori, ML; Kim, Y; Moore, JH; Rich, SS; Mychaleckyj, JC; Kikyo, N; Mauer, M,期刊:Diabetes, 页码:739-744 , 文章类型: Article,,卷期:2012年61-3]
- Clinical studies suggest metabolic memory to hyperglycemia. We tested whether diabetes leads to persistent systematic in vitro gene expression alterations in patients with type 1 diabetes (T1D) compared with their monozy...
- Genetic Predisposition to Dyslipidemia and Type 2 Diabetes Risk in Two Prospective Cohorts
[作者:Qi, QB; Liang, LM; Doria, A; Hu, FB; Qi, L,期刊:Diabetes, 页码:745-752 , 文章类型: Article,,卷期:2012年61-3]
- Dyslipidemia has been associated with type 2 diabetes, but it remains unclear whether dyslipidemia plays a causal role in type 2 diabetes. We aimed to examine the association between the genetic predisposition to dyslipd...
- Effects of Non-HLA Gene Polymorphisms on Development of Islet Autoimmunity and Type 1 Diabetes in a Population With High-Risk HLA-DR,DQ Genotypes
[作者:Steck, AK; Wong, RD; Wagner, B; Johnson, K; Liu, EW; Romanos, J; Wijmenga, C; Norris, JM; Eisenbarth, GS; Rewers, MJ,期刊:Diabetes, 页码:753-758 , 文章类型: Article,,卷期:2012年61-3]
- We assessed the effects of non-HLA gene polymorphisms on the risk of islet autoimmunity (IA) and progression to type 1 diabetes in the Diabetes Autoimmunity Study in the Young. A total of 1,743 non-Hispanic, white childr...
- High glucose attenuates protein S-nitrosylation in endothelial cells: role of oxidative stress (vol 56, pg 2715, 2007)
[作者:Wadham, C; Parker, A; Wang, L; Xia, P,期刊:Diabetes, 页码:759-759 , 文章类型: Correction,,卷期:2012年61-3]
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