Diabetes————————个性化文献订阅—

Glucagon-Like Peptide 1 Recruits Microvasculature and Increases Glucose Use in Muscle via a Nitric Oxide-Dependent Mechanism
[作者：Chai, WD; Dong, ZH; Wang, NS; Wang, WH; Tao, LJ; Cao, WH; Liu, ZQ,期刊：Diabetes, 页码：888-896 , 文章类型： Article，,卷期：2012年61-4]
Glucagon-like peptide 1 (GLP-1) increases tissue glucose uptake and causes vasodilation independent of insulin. We examined the effect of GLP-1 on muscle microvasculature and glucose uptake. After confirming that GLP-1 p...

Cholecystokinin Plays a Novel Protective Role in Diabetic Kidney Through Anti-inflammatory Actions on Macrophage Anti-inflammatory Effect of Cholecystokinin
[作者：Miyamoto, S; Shikata, K; Miyasaka, K; Okada, S; Sasaki, M; Kodera, R; Hirota, D; Kajitani, N; Takatsuka, T; Kataoka, HU; Nishishita, S; Sato, C; Funakoshi, A; Nishimori, H; Uchida, HA; Ogawa, D; Makino, H,期刊：Diabetes, 页码：897-907 , 文章类型： Article，,卷期：2012年61-4]
Inflammatory process is involved in the pathogenesis of diabetic nephropathy. In this article, we show that cholecystokinin (CCK) is expressed in the kidney and exerts renoprotective effects through its anti-inflammatory...

Endothelial Progenitor Cells Carrying Monocyte Markers Are Selectively Abnormal in Type 1 Diabetic Patients With Early Retinopathy
[作者：Zerbini, G; Maestroni, A; Palini, A; Tremolada, G; Lattanzio, R; Maestroni, S; Pastore, MR; Secchi, A; Bonfanti, R; Gerhardinger, C; Lorenzi, M,期刊：Diabetes, 页码：908-914 , 文章类型： Article，,卷期：2012年61-4]
Endothelial progenitor cells (EPCs) enter the systemic circulation in response to cues related to vascular damage and need for neovascularization. Thus, EPCs could become readily accessible informers of vascular status a...

Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis
[作者：Rajwani, A; Ezzat, V; Smith, J; Yuldasheva, NY; Duncan, ER; Gage, M; Cubbon, RM; Kahn, MB; Imrie, H; Abbas, A; Viswambharan, H; Aziz, A; Sukumar, P; Vidal-Puig, A; Sethi, JK; Xuan, SH; Shah, AM; Grant, PJ; Porter, KE; Kearney, MT; Wheatcroft, SB,期刊：Diabetes, 页码：915-924 , 文章类型： Article，,卷期：2012年61-4]
Low concentrations of insulin-like growth factor (IGF) binding protein-1 (IGFBP1) are associated with insulin resistance, diabetes, and cardiovascular disease. We investigated whether increasing IGFBP1 levels can prevent...

Candesartan Cilexetil Improves Angiotensin II Type 2 Receptor-Mediated Neurite Outgrowth via the PI3K-Akt Pathway in Fructose-Induced Insulin-Resistant Rats
[作者：Hashikawa-Hobara, N; Hashikawa, N; Inoue, Y; Sanda, H; Zamami, Y; Takatori, S; Kawasaki, H,期刊：Diabetes, 页码：925-932 , 文章类型： Article，,卷期：2012年61-4]
We have shown previously that stimulation of the angiotensin type 2 receptor (AT(2)R) results in nerve facilitation. In this study, we determined the capacity of candesartan to correct expression patterns characteristic ...

Sustained Antidiabetic Effects of a Berberine-Containing Chinese Herbal Medicine Through Regulation of Hepatic Gene Expression
[作者：Zhao, HL; Sui, Y; Qiao, CF; Yip, KY; Leung, RKK; Tsui, SKW; Lee, HM; Wong, HKT; Zhu, X; Siu, JJ; He, L; Guan, J; Liu, LZ; Xu, HX; Tong, PCY; Chan, JCN,期刊：Diabetes, 页码：933-943 , 文章类型： Article，,卷期：2012年61-4]
Diabetes and obesity are complex diseases associated with insulin resistance and fatty liver. The latter is characterized by dysregulation of the Akt, AMP-activated protein kinase (AMPK), and IGF-I pathways and expressio...

Metformin Prevents the Development of Chronic Heart Failure in the SHHF Rat Model
[作者：Cittadini, A; Napoli, R; Monti, MG; Rea, D; Longobardi, S; Netti, PA; Walser, M; Sama, M; Aimaretti, G; Isgaard, J; Sacca, L,期刊：Diabetes, 页码：944-953 , 文章类型： Article，,卷期：2012年61-4]
Insulin resistance is a recently identified mechanism involved in the pathophysiology of chronic heart failure (CHF). We investigated the effects of two insulin-sensitizing drugs (metformin and rosiglitazone) in a geneti...

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression
[作者：Bergholdt, R; Brorsson, C; Palleja, A; Berchtold, LA; Floyel, T; Bang-Berthelsen, CH; Frederiksen, KS; Jensen, LJ; Storling, J; Pociot, F,期刊：Diabetes, 页码：954-962 , 文章类型： Article，,卷期：2012年61-4]
Genome-wide association studies (GWAS) have heralded a new era in susceptibility locus discovery in complex diseases. For type 1 diabetes, >40 susceptibility loci have been discovered. However, GWAS do not inevitably lea...

Effect of the PTPN22 and INS Risk Genotypes on the Progression to Clinical Type 1 Diabetes After the Initiation of beta-Cell Autoimmunity
[作者：Lempainen, J; Hermann, R; Veijola, R; Simell, O; Knip, M; Ilonen, J,期刊：Diabetes, 页码：963-966 , 文章类型： Article，,卷期：2012年61-4]
We set out to analyze the role of two major non-HLA gene polymorphisms associated with type 1 diabetes (T1D), PTPN22 1858C/T and insulin gene INS-23 A/T in progression to clinical T1D after the appearance of beta-cell au...

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