- CENP-T-W-S-X Forms a Unique Centromeric Chromatin Structure with a Histone-like Fold
[作者：Nishino, T; Takeuchi, K; Gascoigne, KE; Suzuki, A; Hori, T; Oyama, T; Morikawa, K; Cheeseman, IM; Fukagawa, T,期刊：Cell, 页码：487-501 , 文章类型： Article，,卷期：2012年148-3]
- The multiprotein kinetochore complex must assemble at a specific site on each chromosome to achieve accurate chromosome segregation. Defining the nature of the DNA-protein interactions that specify the position of the ki...
- Cortical Dynein Controls Microtubule Dynamics to Generate Pulling Forces that Position Microtubule Asters
[作者：Laan, L; Pavin, N; Husson, J; Romet-Lemonne, G; van Duijn, M; Lopez, MP; Vale, RD; Julicher, F; Reck-Peterson, SL; Dogterom, M,期刊：Cell, 页码：502-514 , 文章类型： Article，,卷期：2012年148-3]
- Dynein at the cortex contributes to microtubule-based positioning processes such as spindle positioning during embryonic cell division and centrosome positioning during fibroblast migration. To investigate how cortical d...
- Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory
[作者：Majumdar, A; Cesario, WC; White-Grindley, E; Jiang, HQ; Ren, FZ; Khan, M; Li, LY; Choi, EML; Kannan, K; Guo, FL; Unruh, J; Slaughter, B; Si, K,期刊：Cell, 页码：515-529 , 文章类型： Article，,卷期：2012年148-3]
- A long-standing question in the study of long-term memory is how a memory trace persists for years when the proteins that initiated the process turn over and disappear within days. Previously, we postulated that self-sus...
- PKC epsilon Promotes Oncogenic Functions of ATF2 in the Nucleus while Blocking Its Apoptotic Function at Mitochondria
[作者：Lau, E; Kluger, H; Varsano, T; Lee, K; Scheffler, I; Rimm, DL; Ideker, T; Ronai, ZA,期刊：Cell, 页码：543-555 , 文章类型： Article，,卷期：2012年148-3]
- The transcription factor ATF2 elicits oncogenic activities in melanoma and tumor suppressor activities in nonmalignant skin cancer. Here, we identify that ATF2 tumor suppressor function is determined by its ability to lo...
- Fibroblast Growth Factor-21 Regulates PPAR gamma Activity and the Antidiabetic Actions of Thiazolidinediones
[作者：Dutchak, PA; Katafuchi, T; Bookout, AL; Choi, JH; Yu, RT; Mangelsdorf, DJ; Kliewer, SA,期刊：Cell, 页码：556-567 , 文章类型： Article，,卷期：2012年148-3]
- Fibroblast growth factor-21 (FGF21) is a circulating hepatokine that beneficially affects carbohydrate and lipid metabolism. Here, we report that FGF21 is also an inducible, fed-state autocrine factor in adipose tissue t...
- Ret Is a Multifunctional Coreceptor that Integrates Diffusible- and Contact-Axon Guidance Signals
[作者：Bonanomi, D; Chivatakarn, O; Bai, G; Abdesselem, H; Lettieri, K; Marquardt, T; Pierchala, BA; Pfaff, SL,期刊：Cell, 页码：568-582 , 文章类型： Article，,卷期：2012年148-3]
- Growing axons encounter multiple guidance cues, but it is unclear how separate signals are resolved and integrated into coherent instructions for growth cone navigation. We report that glycosylphosphati-dylinositol (GPI)...
- Visualizing Neuromodulation In Vivo: TANGO-Mapping of Dopamine Signaling Reveals Appetite Control of Sugar Sensing
[作者：Inagaki, HK; De-Leon, SBT; Wong, AM; Jagadish, S; Ishimoto, H; Barnea, G; Kitamoto, T; Axel, R; Anderson, DJ,期刊：Cell, 页码：583-595 , 文章类型： Article，,卷期：2012年148-3]
- Behavior cannot be predicted from a "connectome'' because the brain contains a chemical "map'' of neuromodulation superimposed upon its synaptic connectivity map. Neuromodulation changes how neural circuits process infor...
- Modular Genetic Control of Sexually Dimorphic Behaviors
[作者：Xu, XH; Coats, JK; Yang, CF; Wang, A; Ahmed, OM; Alvarado, M; Izumi, T; Shah, NM,期刊：Cell, 页码：596-607 , 文章类型： Article，,卷期：2012年148-3]
- Sex hormones such as estrogen and testosterone are essential for sexually dimorphic behaviors in vertebrates. However, the hormone-activated molecular mechanisms that control the development and function of the underlyin...
- Optimality in the Development of Intestinal Crypts
[作者：Itzkovitz, S; Blat, IC; Jacks, T; Clevers, H; van Oudenaarden, A,期刊：Cell, 页码：608-619 , 文章类型： Article，,卷期：2012年148-3]
- Intestinal crypts in mammals are comprised of long-lived stem cells and shorter-lived progenies. These two populations are maintained in specific proportions during adult life. Here, we investigate the design principles ...
|