- Hyaluronan Synthase HAS2 Promotes Tumor Progression in Bone by Stimulating the Interaction of Breast Cancer Stem-Like Cells with Macrophages and Stromal Cells
[作者:Okuda, H; Kobayashi, A; Xia, B; Watabe, M; Pai, SK; Hirota, S; Xing, F; Liu, W; Pandey, PR; Fukuda, K; Modur, V; Ghosh, A; Wilber, A; Watabe, K,期刊:Cancer research, 页码:537-547 , 文章类型: Article,,卷期:2012年72-2]
- The molecular mechanisms that operate within the organ microenvironment to support metastatic progression remain unclear. Here, we report that upregulation of hyaluronan synthase 2 (HAS2) occurs in highly metastatic brea...
- Metastatic Progression with Resistance to Aromatase Inhibitors Is Driven by the Steroid Receptor Coactivator SRC-1
[作者:McBryan, J; Theissen, SM; Byrne, C; Hughes, E; Cocchiglia, S; Sande, S; O'Hara, J; Tibbitts, P; Hill, ADK; Young, LS,期刊:Cancer research, 页码:548-559 , 文章类型: Article,,卷期:2012年72-2]
- Aromatase inhibitors (AI) are a standard-of-care treatment for postmenopausal, estrogen receptor-positive breast cancers. Although tumor recurrence on AI therapy occurs, the mechanisms underlying acquired resistance to A...
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