个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共28条记录   Cathepsin B Inhibition Limits Bone Metastasis in Breast Cancer [作者：Withana, NP; Blum, G; Sameni, M; Slaney, C; Anbalagan, A; Olive, MB; Bidwell, BN; Edgington, L; Wang, L; Moin, K; Sloane, BF; Anderson, RL; Bogyo, MS; Parker, BS,期刊：Cancer research, 页码：1199-1209 , 文章类型： Article，,卷期：2012年72-5] Metastasis to bone is a major cause of morbidity in breast cancer patients, emphasizing the importance of identifying molecular drivers of bone metastasis for new therapeutic targets. The endogenous cysteine cathepsin in... B Effector Cells Activated by a Chimeric Protein Consisting of IL-2 and the Ectodomain of TGF-beta Receptor II Induce Potent Antitumor Immunity [作者：Penafuerte, C; Ng, S; Bautista-Lopez, N; Birman, E; Forner, K; Galipeau, J,期刊：Cancer research, 页码：1210-1220 , 文章类型： Article，,卷期：2012年72-5] We have previously shown that interleukin (IL)-2 receptor-expressing lymphoid cells stimulated with a chimeric protein linking IL-2 to the ectodomain of TGF-beta receptor II (also known as FIST) become resistant to TGF-b... RNAi-Mediated Targeting of Noncoding and Coding Sequences in DNA Repair Gene Messages Efficiently Radiosensitizes Human Tumor Cells [作者：Zheng, ZM; Ng, WL; Zhang, XM; Olson, JJ; Hao, CH; Curran, WJ; Wang, Y,期刊：Cancer research, 页码：1221-1228 , 文章类型： Article，,卷期：2012年72-5] Human tumor cell death during radiotherapy is caused mainly by ionizing radiation (IR)-induced DNA double-strand breaks (DSB), which are repaired by either homologous recombination repair (HRR) or nonhomologous end-joini... LRIG1 Modulates Cancer Cell Sensitivity to Smac Mimetics by Regulating TNF alpha Expression and Receptor Tyrosine Kinase Signaling [作者：Bai, LC; McEachern, D; Yang, CY; Lu, JF; Sun, HY; Wang, SM,期刊：Cancer research, 页码：1229-1238 , 文章类型： Article，,卷期：2012年72-5] Smac mimetics block inhibitor of apoptosis proteins to trigger TNF alpha-dependent apoptosis in cancer cells. However, only a small subset of cancer cells seem to be sensitive to Smac mimetics and even sensitive cells ca... Adoptive Cell Therapy for Lymphoma with CD4 T Cells Depleted of CD137-Expressing Regulatory T Cells [作者：Goldstein, MJ; Kohrt, HE; Houot, R; Varghese, B; Lin, JT; Swanson, E; Levy, R,期刊：Cancer research, 页码：1239-1247 , 文章类型： Article，,卷期：2012年72-5] Adoptive immunotherapy with antitumor T cells is a promising novel approach for the treatment of cancer. However, T-cell therapy may be limited by the cotransfer of regulatory T cells (T-reg). Here, we explored this hypo... Targeting Pioneering Factor and Hormone Receptor Cooperative Pathways to Suppress Tumor Progression [作者：Shah, S; Prasad, S; Knudsen, KE,期刊：Cancer research, 页码：1248-1259 , 文章类型： Article，,卷期：2012年72-5] Nuclear receptors and pioneer factors drive the development and progression of prostate cancer. In this disease, aggressive disease phenotypes and hormone therapy failures result from resurgent activity of androgen recep... PRAS40 Is a Functionally Critical Target for EWS Repression in Ewing Sarcoma [作者：Huang, L; Nakai, YJ; Kuwahara, I; Matsumoto, K,期刊：Cancer research, 页码：1260-1269 , 文章类型： Article，,卷期：2012年72-5] Ewing sarcoma family tumors (ESFT) are highly aggressive and highly metastatic tumors caused by a chromosomal fusion between the Ewing sarcoma protein (EWS) with the transcription factor FLI-1. However, expression of the... p53 Inhibits Angiogenesis by Inducing the Production of Arresten [作者：Assadian, S; El-Assaad, W; Wang, XQD; Gannon, PO; Barres, V; Latour, M; Mes-Masson, AM; Saad, F; Sado, Y; Dostie, J; Teodoro, JG,期刊：Cancer research, 页码：1270-1279 , 文章类型： Article，,卷期：2012年72-5] Several types of collagen contain cryptic antiangiogenic noncollagenous domains that are released upon proteolysis of extracellular matrix (ECM). Among those is Arresten, a collagen-derived antiangiogenic factor (CDAF) t... Pocket Proteins Suppress Head and Neck Cancer [作者：Shin, MK; Pitot, HC; Lambert, PF,期刊：Cancer research, 页码：1280-1289 , 文章类型： Article，,卷期：2012年72-5] Head and neck squamous cell carcinomas (HNSCC) is a common cancer in humans long known to be caused by tobacco and alcohol use, but now an increasing percentage of HNSCC is recognized to be caused by the same human papil... Epithelial-Mesenchymal Transition Induced by TNF-alpha Requires NF-kappa B-Mediated Transcriptional Upregulation of Twist1 [作者：Li, CW; Xia, WY; Huo, LF; Lim, SO; Wu, Y; Hsu, JL; Chao, CH; Yamaguchi, H; Yang, NK; Ding, QQ; Wang, Y; Lai, YJ; LaBaff, AM; Wu, TJ; Lin, BR; Yang, MH; Hortobagyi, GN; Hung, MC,期刊：Cancer research, 页码：1290-1300 , 文章类型： Article，,卷期：2012年72-5] Proinflammatory cytokines produced in the tumor microenvironment facilitate tumor development and metastatic progression. In particular, TNF-alpha promotes cancer invasion and angiogenesis associated with epithelial-mese... Oncogenicity of the Developmental Transcription Factor Sox9 [作者：Matheu, A; Collado, M; Wise, C; Manterola, L; Cekaite, L; Tye, AJ; Canamero, M; Bujanda, L; Schedl, A; Cheah, KSE; Skotheim, RI; Lothe, RA; de Munain, AL; Briscoe, J; Serrano, M; Lovell-Badge, R,期刊：Cancer research, 页码：1301-1315 , 文章类型： Article，,卷期：2012年72-5] SOX9[ sex-determining region Y (SRY)-box 9 protein], a high mobility group box transcription factor, plays critical roles during embryogenesis and its activity is required for development, differentiation, and lineage co... Concomitant Tumor Resistance: The Role of Tyrosine Isomers in the Mechanisms of Metastases Control [作者：Ruggiero, RA; Bruzzo, J; Chiarella, P; Bustuoabad, OD; Meiss, RP; Pasqualini, CD,期刊：Cancer research, 页码：1043-1050 , 文章类型： Review，,卷期：2012年72-5] Concomitant tumor resistance (CR) is a phenomenon in which a tumor-bearing host is resistant to the growth of secondary tumor implants and metastasis. Although previous studies indicated that T-cell-dependent processes m...