- The relationship between tissue factor and cancer progression: insights from bench and bedside
[作者:van den Berg, YW; Osanto, S; Reitsma, PH; Versteeg, HH,期刊:Blood, 页码:924-932 , 文章类型: Review,,卷期:2012年119-4]
- It is now widely recognized that a strong correlation exists between cancer and aberrant hemostasis. Patients with various types of cancers, including pancreatic, colorectal, and gastric cancer, often develop thrombosis,...
- Aspirin or enoxaparin thromboprophylaxis for patients with newly diagnosed multiple myeloma treated with lenalidomide
[作者:Larocca, A; Cavallo, F; Bringhen, S; Di Raimondo, F; Falanga, A; Evangelista, A; Cavalli, M; Stanevsky, A; Corradini, P; Pezzatti, S; Patriarca, F; Cavo, M; Peccatori, J; Catalano, L; Carella, AM; Cafro, AM; Siniscalchi, A; Crippa, C; Petrucci, MT; Ben Yehuda, D; Beggiato, E; Di Toritto, TC; Boccadoro, M; Nagler, A; Palumbo, A,期刊:Blood, 页码:933-939 , 文章类型: Article,,卷期:2012年119-4]
- Lenalidomide plus dexamethasone is effective in the treatment of multiple myeloma (MM) but is associated with an increased risk of venous thromboembolism (VTE). This prospective, open-label, randomized substudy of a phas...
- Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p
[作者:Neben, K; Lokhorst, HM; Jauch, A; Bertsch, U; Hielscher, T; van der Holt, B; Salwender, H; Blau, IW; Weisel, K; Pfreundschuh, M; Scheid, C; Duhrsen, U; Lindemann, W; Schmidt-Wolf, IGH; Peter, N; Teschendorf, C; Martin, H; Haenel, M; Derigs, HG; Raab, MS; Ho, AD; van de Velde, H; Hose, D; Sonneveld, P; Goldschmidt, H,期刊:Blood, 页码:940-948 , 文章类型: Article,,卷期:2012年119-4]
- In patients with multiple myeloma (MM), risk stratification by chromosomal abnormalities may enable a more rational selection of therapeutic approaches. In the present study, we analyzed the prognostic value of 12 chromo...
- Safety of anticoagulants in children with arterial ischemic stroke
[作者:Schechter, T; Kirton, A; Laughlin, S; Pontigon, AM; Finkelstein, Y; MacGregor, D; Chan, A; deVeber, G; Brandao, LR,期刊:Blood, 页码:949-956 , 文章类型: Article,,卷期:2012年119-4]
- Pediatric arterial ischemic stroke (AIS) is increasingly diagnosed and carries significant risks of recurrence, morbidity, and mortality. Anticoagulant therapy (ACT) is commonly prescribed in childhood AIS. Hemorrhagic c...
- AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage
[作者:Binny, C; McIntosh, J; Della Peruta, M; Kymalainen, H; Tuddenham, EGD; Buckley, SMK; Waddington, SN; McVey, JH; Spence, Y; Morton, CL; Thrasher, AJ; Gray, JT; Castellino, FJ; Tarantal, AF; Davidoff, AM; Nathwani, AC,期刊:Blood, 页码:957-966 , 文章类型: Article,,卷期:2012年119-4]
- We explored adeno-associated viral vector (AAV) mediated gene transfer in the perinatal period in animal models of severe congenital factor VII (FVII) deficiency, a disease associated with early postnatal life-threatenin...
- TLR3 essentially promotes protective class I-restricted memory CD8(+) T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients
[作者:Carvalho, A; De Luca, A; Bozza, S; Cunha, C; D'Angelo, C; Moretti, S; Perruccio, K; Iannitti, RG; Fallarino, F; Pierini, A; Latge, JP; Velardi, A; Aversa, F; Romani, L,期刊:Blood, 页码:967-977 , 文章类型: Article,,卷期:2012年119-4]
- Aspergillus fumigatus is a model fungal pathogen and a common cause of severe infections and diseases. CD8(+) T cells are present in the human and murine T-cell repertoire to the fungus. However, CD8(+) T-cell function i...
- Lymph node B lymphocyte trafficking is constrained by anatomy and highly dependent upon chemoattractant desensitization
[作者:Park, C; Hwang, IY; Sinha, RK; Kamenyeva, O; Davis, MD; Kehrl, JH,期刊:Blood, 页码:978-989 , 文章类型: Article,,卷期:2012年119-4]
- B lymphocyte recirculation through lymph nodes (LNs) requires crossing endothelial barriers and chemoattractant-triggered cell migration. Here we show how LN anatomy and chemoattractant receptor signaling organize B lymp...
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