- How I treat childhood CML
[作者：Andolina, JR; Neudorf, SM; Corey, SJ,期刊：Blood, 页码：1821-1830 , 文章类型： Article，,卷期：2012年119-8]
- Chronic myeloid leukemia (CML) is composed of 3% of pediatric leukemias, making evidence-based recommendations difficult. Imatinib has revolutionized the treatment for adult CML by eliminating allogeneic stem cell transp...
- The strategy for the diagnosis of invasive pulmonary aspergillosis should depend on both the underlying condition and the leukocyte count of patients with hematologic malignancies
[作者：Bergeron, A; Porcher, R; Sulahian, A; de Bazelaire, C; Chagnon, K; Raffoux, E; Vekhoff, A; Cornet, M; Isnard, F; Brethon, B; Lacroix, C; Poirot, JL; Bouges, C; Derouin, F; Tazi, A; Ribaud, P,期刊：Blood, 页码：1831-1837 , 文章类型： Article，,卷期：2012年119-8]
- The identification of the causative organism in invasive pulmonary aspergillosis (IPA) is recommended. We investigated whether a mycologic diagnostic strategy could be optimized based on patient characteristics. Fifty-fi...
- Responses to second-line tyrosine kinase inhibitors are durable: an intention-to-treat analysis in chronic myeloid leukemia patients
[作者：Milojkovic, D; Apperley, JF; Gerrard, G; Ibrahim, AR; Szydlo, R; Bua, M; Reid, A; Rezvani, K; Foroni, L; Goldman, J; Marin, D,期刊：Blood, 页码：1838-1843 , 文章类型： Article，,卷期：2012年119-8]
- Second-generation tyrosine kinase inhibitors (2G-TKIs) are effective at inducing complete cytogenetic responses (CCyRs) in approximately half of chronic myeloid leukemia patients treated while still in the chronic phase ...
- Reliable typing of systemic amyloidoses through proteomic analysis of subcutaneous adipose tissue
[作者：Brambilla, F; Lavatelli, F; Di Silvestre, D; Valentini, V; Rossi, R; Palladini, G; Obici, L; Verga, L; Mauri, P; Merlini, G,期刊：Blood, 页码：1844-1847 , 文章类型： Article，,卷期：2012年119-8]
- Considering the important advances in treating specific types of systemic amyloidoses, unequivocal typing of amyloid deposits is now essential. Subcutaneous abdominal fat aspiration is the easiest, most common diagnostic...
- Bone marrow homing and engraftment of human hematopoietic stem and progenitor cells is mediated by a polarized membrane domain
[作者：Larochelle, A; Gillette, JM; Desmond, R; Ichwan, B; Cantilena, A; Cerf, A; Barrett, AJ; Wayne, AS; Lippincott-Schwartz, J; Dunbar, CE,期刊：Blood, 页码：1848-1855 , 文章类型： Article，,卷期：2012年119-8]
- Manipulation of hematopoietic stem/progenitor cells (HSPCs) ex vivo is of clinical importance for stem cell expansion and gene therapy applications. However, most cultured HSPCs are actively cycling, and show a homing an...
- SIRT1 is dispensable for function of hematopoietic stem cells in adult mice
[作者：Leko, V; Varnum-Finney, B; Li, HZ; Gu, YS; Flowers, D; Nourigat, C; Bernstein, ID; Bedalov, A,期刊：Blood, 页码：1856-1860 , 文章类型： Article，,卷期：2012年119-8]
- SIRT1 is an NAD(+)-dependent histone deacetylase implicated in the establishment of the primitive hematopoietic system during mouse embryonic development. However, investigation of the role of SIRT1 in adult hematopoiesi...
- Expression of BMPRIA on human thymic NK cell precursors: role of BMP signaling in intrathymic NK cell development
[作者：Hidalgo, L; Martinez, VG; Valencia, J; Hernandez-Lopez, C; Vazquez, MN; Nunez, JR; Zapata, AG; Sacedon, R; Varas, A; Vicente, A,期刊：Blood, 页码：1861-1871 , 文章类型： Article，,卷期：2012年119-8]
- The bone morphogenetic protein (BMP) signaling pathway regulates survival, proliferation, and differentiation of several cell types in multiple tissues, including the thymus. Previous reports have shown that BMP signalin...
- Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study
[作者：Kang, HN; Wilson, CS; Harvey, RC; Chen, IM; Murphy, MH; Atlas, SR; Bedrick, EJ; Devidas, M; Carroll, AJ; Robinson, BW; Stam, RW; Valsecchi, MG; Pieters, R; Heerema, NA; Hilden, JM; Felix, CA; Reaman, GH; Camitta, B; Winick, N; Carroll, WL; Dreyer, ZE; Hunger, SP; Willman, CL,期刊：Blood, 页码：1872-1881 , 文章类型： Article，,卷期：2012年119-8]
- Gene expression profiling was performed on 97 cases of infant ALL from Children's Oncology Group Trial P9407. Statistical modeling of an outcome predictor revealed 3 genes highly predictive of event-free survival (EFS), ...
- Patient age at diagnosis is associated with the molecular characteristics of diffuse large B-cell lymphoma
[作者：Klapper, W; Kreuz, M; Kohler, CW; Burkhardt, B; Szczepanowski, M; Salaverria, I; Hummel, M; Loeffler, M; Pellissery, S; Woessmann, W; Schwanen, C; Trumper, L; Wessendorf, S; Spang, R; Hasenclever, D; Siebert, R,期刊：Blood, 页码：1882-1887 , 文章类型： Article，,卷期：2012年119-8]
- Diffuse large B-cell lymphoma is the most frequent type of B-cell lymphoma in adult patients but also occurs in children. Patients are currently assigned to therapy regimens based on arbitrarily chosen age limits only (e...
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