- e-Blood Microscale functional cytomics for studying hematologic cancers
[作者：Young, EWK; Pak, C; Kahl, BS; Yang, DT; Callander, NS; Miyamoto, S; Beebe, DJ,期刊：Blood, 页码：E76-E85 , 文章类型： Editorial Material，,卷期：2012年119-10]
- An important problem in translational cancer research is our limited ability to functionally characterize behaviors of primary patient cancer cells and associated stromal cell types, and relate mechanistic understanding ...
- Targeting hedgehog in hematologic malignancy
[作者：Irvine, DA; Copland, M,期刊：Blood, 页码：2196-2204 , 文章类型： Review，,卷期：2012年119-10]
- The Hedgehog pathway is a critical mediator of embryonic patterning and organ development, including hematopoiesis. It influences stem cell fate, differentiation, proliferation, and apoptosis in responsive tissues. In ad...
- How I treat heparin-induced thrombocytopenia
[作者：Cuker, A; Cines, DB,期刊：Blood, 页码：2209-2218 , 文章类型： Article，,卷期：2012年119-10]
- Heparin-induced thrombocytopenia is a prothrombotic adverse drug effect induced by platelet-activating antibodies against multimolecular complexes of platelet factor 4 and heparin. Diagnosis rests on a clinical assessmen...
- Thrombocythemia and polycythemia in patients younger than 20 years at diagnosis: clinical and biologic features, treatment, and long-term outcome
[作者：Giona, F; Teofili, L; Moleti, ML; Martini, M; Palumbo, G; Amendola, A; Mazzucconi, MG; Testi, AM; Pignoloni, P; Orlando, SM; Capodimonti, S; Nanni, M; Leone, G; Larocca, LM; Foa, R,期刊：Blood, 页码：2219-2227 , 文章类型： Article，,卷期：2012年119-10]
- Sixty-four patients < 20 years of age, investigated for a suspicion of Philadelphia-negative myeloproliferative disease (MPD), were retrospectively evaluated to characterize the different forms and to examine the treatme...
- Rituximab decreases the risk of lymphoma in patients with HIV-associated multicentric Castleman disease
[作者：Gerard, L; Michot, JM; Burcheri, S; Fieschi, C; Longuet, P; Delcey, V; Meignin, V; Agbalika, F; Chevret, S; Oksenhendler, E; Galicier, L,期刊：Blood, 页码：2228-2233 , 文章类型： Article，,卷期：2012年119-10]
- HIV-associated multicentric Castleman disease (MCD) is associated with a high risk of developing nonHodgkin lymphoma (NHL). Rituximab is effective in HIV-MCD, but its impact on NHL incidence remains unknown. From a singl...
- Brief report Poor response to second-line kinase inhibitors in chronic myeloid leukemia patients with multiple low-level mutations, irrespective of their resistance profile
[作者：Parker, WT; Ho, MS; Scott, HS; Hughes, TP; Branford, S,期刊：Blood, 页码：2234-2238 , 文章类型： Article，,卷期：2012年119-10]
- Specific imatinib-resistant BCR-ABL1 mutations (Y253H, E255K/V, T315I, F317L, and F359V/C) predict failure of second-line nilotinib or dasatinib therapy in patients with chronic myeloid leukemia; however, such therapy al...
- Brief report Initial bone marrow reticulin fibrosis in polycythemia vera exerts an impact on clinical outcome
[作者：Barbui, T; Thiele, J; Passamonti, F; Rumi, E; Boveri, E; Randi, ML; Bertozzi, I; Marino, F; Vannucchi, AM; Pieri, L; Rotunno, G; Gisslinger, H; Gisslinger, B; Mullauer, L; Finazzi, G; Carobbio, A; Gianatti, A; Ruggeri, M; Nichele, I; D'Amore, E; Rambaldi, A; Tefferi, A,期刊：Blood, 页码：2239-2241 , 文章类型： Article，,卷期：2012年119-10]
- We examined the prevalence and prognostic relevance of bone marrow reticulin fibrosis in 526 patients with World Health Organization-defined polycythemia vera evaluated at the time of initial diagnosis. Seventy-four pati...
- PIP2-dependent regulation of Munc13-4 endocytic recycling: impact on the cytolytic secretory pathway
[作者：Capuano, C; Paolini, R; Molfetta, R; Frati, L; Santoni, A; Galandrini, R,期刊：Blood, 页码：2252-2262 , 文章类型： Article，,卷期：2012年119-10]
- Cytotoxic lymphocytes clear infected and transformed cells by releasing the content of lytic granules at cytolytic synapses, and the ability of cytolytic effectors to kill in an iterative manner has been documented previ...
- CIN85 is required for Cbl-mediated regulation of antigen receptor signaling in human B cells
[作者：Niiro, H; Jabbarzadeh-Tabrizi, S; Kikushige, Y; Shima, T; Noda, K; Ota, S; Tsuzuki, H; Inoue, Y; Arinobu, Y; Iwasaki, H; Shimoda, S; Baba, E; Tsukamoto, H; Horiuchi, T; Taniyama, T; Akashi, K,期刊：Blood, 页码：2263-2273 , 文章类型： Article，,卷期：2012年119-10]
- The aberrant regulation of B-cell receptor (BCR) signaling allows unwanted B cells to persist, thereby potentially leading to autoimmunity and B-cell malignancies. Casitas B-lineage lymphoma (Cbl) proteins suppress BCR s...
- HIV-1 matrix protein p17 binds to the IL-8 receptor CXCR1 and shows IL-8-like chemokine activity on monocytes through Rho/ROCK activation
[作者：Giagulli, C; Magiera, AK; Bugatti, A; Caccuri, F; Marsico, S; Rusnati, M; Vermi, W; Fiorentini, S; Caruso, A,期刊：Blood, 页码：2274-2283 , 文章类型： Article，,卷期：2012年119-10]
- Exogenous HIV-1 matrix protein p17 was found to deregulate biologic activities of many different immune cells that are directly or indirectly involved in AIDS pathogenesis after binding to unknown cellular receptor(s). I...
|