- Sequence Effects on Translesion Synthesis of an Aminofluorene-DNA Adduct: Conformational, Thermodynamic, and Primer Extension Kinetic Studies
[作者:Vaidyanathan, VG; Cho, BP,期刊:Biochemistry, 页码:1983-1995 , 文章类型: Article,,卷期:2012年51-9]
- The DNA sequence effect is an important structural factor for determining the extent and nature of carcinogen-induced mutational and repair outcomes. In this study, we used two 16-mer template sequences, TG*A [d(5'-CTTCT...
- APOBEC2 Is a Monomer in Solution: Implications for APOBEC3G Models
[作者:Krzysiak, TC; Jung, J; Thompson, J; Baker, D; Gronenborn, AM,期刊:Biochemistry, 页码:2008-2017 , 文章类型: Article,,卷期:2012年51-9]
- Although the physiological role of APOBEC2 is still largely unknown, a crystal structure of a truncated variant of this protein was determined several years ago [Prochnow, C. (2007) Nature 445, 447-451]. This APOBEC2 str...
- Thermodynamic Signature of DNA Damage: Characterization of DNA with a 5-Hydroxy-2 '-deoxycytidine center dot 2 '-Deoxyguanosine Base Pair
[作者:Ganguly, M; Szulik, MW; Donahue, PS; Clancy, K; Stone, MP; God, B,期刊:Biochemistry, 页码:2018-2027 , 文章类型: Article,,卷期:2012年51-9]
- Oxidation of DNA due to exposure to reactive oxygen species is a major source of DNA damage. One of the oxidation lesions formed, 5-hydroxy-2'-deoxycytidine, has been shown to miscode by some replicative DNA polymerases ...
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