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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共18条记录   Click Dimers To Target HIV TAR RNA Conformation [作者：Kumar, S; Kellish, P; Robinson, WE; Wang, DY; Appella, DH; Arya, DP,期刊：Biochemistry, 页码：2331-2347 , 文章类型： Article，,卷期：2012年51-11] A series of neomycin dimers have been synthesized using "click chemistry" with varying functionality and length in the linker region to target the human immunodeficiency virus type 1 (HIV-1) TAR RNA region of the HIV vir... Observation of Two Modes of Inhibition of Human Microsomal Prostaglandin E Synthase 1 by the Cyclopentenone 15-Deoxy-Delta(12,14)-prostaglandin J(2) [作者：Prage, EB; Morgenstern, R; Jakobsson, PJ; Stec, DF; Voehler, MW; Armstrong, RN,期刊：Biochemistry, 页码：2348-2356 , 文章类型： Article，,卷期：2012年51-11] Microsomal prostaglandin E synthase 1 (MPGES1) is an enzyme that produces the pro-inflammatory molecule prostaglandin E-2 (PGE(2)). Effective inhibitors of MPGES1 are of considerable pharmacological interest for the sele...