- The Ribosome Modulates Nascent Protein Folding
[作者:Kaiser, CM; Goldman, DH; Chodera, JD; Tinoco, I; Bustamante, C,期刊:Science, 页码:1723-1727 , 文章类型: Article,,卷期:2011年334-6063]
- The blood-brain barrier (BBB) is composed of tightly bound endothelial cells (ECs) and perivascular astrocytes that regulate central nervous system (CNS) homeostasis. We showed that astrocytes secrete Sonic hedgehog and ...
- Npas4 Regulates a Transcriptional Program in CA3 Required for Contextual Memory Formation
[作者:Ramamoorthi, K; Fropf, R; Belfort, GM; Fitzmaurice, HL; McKinney, RM; Neve, RL; Otto, T; Lin, YX,期刊:Science, 页码:1669-1675 , 文章类型: Article,,卷期:2011年334-6063]
- The rapid encoding of contextual memory requires the CA3 region of the hippocampus, but the necessary genetic pathways remain unclear. We found that the activity-dependent transcription factor Npas4 regulates a transcrip...
- Mouse B-Type Lamins Are Required for Proper Organogenesis But Not by Embryonic Stem Cells
[作者:Kim, Y; Sharov, AA; McDole, K; Cheng, M; Hao, H; Fan, CM; Gaiano, N; Ko, MSH; Zheng, Y,期刊:Science, 页码:1706-1710 , 文章类型: Article,,卷期:2011年334-6063]
- B-type lamins, the major components of the nuclear lamina, are believed to be essential for cell proliferation and survival. We found that mouse embryonic stem cells (ESCs) do not need any lamins for self-renewal and plu...
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