(3S,4S)-3-Methyloctan-4-ol, (4S,5S)-4-methylnonan-5-ol, and (+)-trans-whiskey lactone [(4S,5R)-5-butyl-4-methyldihydrofuran-2(3H)-one] were synthesized stereoselectively by using a radical cyclization reaction as a key s...
1,1-Diethoxybut-3-yn-2-one, a conjugated terminal acetylenic ketone, reacts with nitrogen and oxygen nucleophiles and gives Michael adducts, in most cases in good to excellent yield. In almost every case the predominant ...
A modular synthesis of highly functionalized unsymmetrical pyridines has been developed from reacting beta-sulfonylvinylamines with alpha,beta-unsaturated systems in the presence of base via the formation of 1-aza-allyl ...
A facile and simple protocol for Ullmann-type N-arylation of nucleobases with aryl halides is described using copper nanoparticle-doped silica cuprous sulfate (CN-DSCS) as a new and efficient heterogeneous catalysis. In ...