- New pharmaceutical applications for macromolecular binders
[作者：Bertrand, N; Gauthier, MA; Bouvet, C; Moreau, P; Petitjean, A; Leroux, JC; Leblond, J,期刊：Journal of controlled release, 页码：200-210 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2]
- Macromolecular binders consist of polymers, dendrimers, and oligomers with binding properties for endogenous or exogenous substrates. This field, at the frontier of host/guest chemistry and pharmacology, has met a renewe...
- Molecular targeting of atherosclerotic plaques by a stabilin-2-specific peptide ligand
[作者：Lee, GY; Kim, JH; Oh, GT; Lee, BH; Kwon, IC; Kim, IS,期刊：Journal of controlled release, 页码：211-217 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2]
- Many cells, including macrophages, accumulate in atherosclerotic lesions, destabilizing plaques and driving plaque disruption. Therefore, macrophages serve as useful targets for atherosclerosis treatment and imaging. Sta...
- Design and cellular internalization of genetically engineered polypeptide nanoparticles displaying adenovirus knob domain
[作者：Sun, GY; Hsueh, PY; Janib, SM; Hamm-Alvarez, S; MacKay, JA,期刊：Journal of controlled release, 页码：218-226 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2]
- Hepatocytes and acinar cells exhibit high-efficiency, fiber-dependent internalization of adenovirus; however, viral capsids have unpredictable immunological effects and are challenging to develop into targeted drug carri...
- Multi-modal strategies for overcoming tumor drug resistance: Hypoxia, the Warburg effect, stem cells, and multifunctional nanotechnology
[作者：Milane, L; Ganesh, S; Shah, S; Duan, ZF; Amiji, M,期刊：Journal of controlled release, 页码：237-247 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2]
- Inefficiencies in systemic drug delivery and tumor residence as well as micro-environmental selection pressures contribute to the development of multidrug resistance (MDR) in cancer. Characteristics of MDR include abnorm...
- Development of docetaxel-loaded intravenous formulation, Nanoxel-PM (TM) using polymer-based delivery system
[作者：Lee, SW; Yun, MH; Jeong, SW; In, CH; Kim, JY; Seo, MH; Pai, CM; Kim, SO,期刊：Journal of controlled release, 页码：262-271 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2]
- Nanoxel-PM (TM), docetaxel-loaded methoxy-poly(ethylene glycol)-block-poly(D, L-lactide) (mPEG-PDLLA) micellar formulation was prepared in an effort to develop alternative, less toxic and efficacious Tween 80-free doceta...
- PEG-oligocholic acid telodendrimer micelles for the targeted delivery of doxorubicin to B-cell lymphoma
[作者：Xiao, K; Luo, JT; Li, YP; Lee, JS; Fung, G; Lam, KS,期刊：Journal of controlled release, 页码：272-281 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2]
- Doxorubicin (DOX) is one of most common anti-cancer chemotherapeutic drugs, but its clinical use is associated with dose-limiting cardiotoxicity. We have recently developed a series of PEG-oligocholic acid based telodend...
- Circulation kinetics and biodistribution of dual-labeled polymersomes with modulated surface charge in tumor-bearing mice: Comparison with stealth liposomes
[作者：Lee, JS; Ankone, M; Pieters, E; Schiffelers, RM; Hennink, WE; Jan, FJ,期刊：Journal of controlled release, 页码：282-288 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2]
- Polymersomes (Ps) based on poly(ethylene glycol)-b-poly(D,L-lactide) (PEG-PDLLA), with similar sizes (90-100 nm), but different zeta potentials (-7.6 to -38.7 mV) were prepared to investigate the effect of surface charge...
- A strategy to deliver genes to cystic fibrosis lungs: A battle with environment
[作者：Ibrahim, BM; Park, S; Han, B; Yeo, Y,期刊：Journal of controlled release, 页码：289-295 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2]
- Cystic fibrosis (CF) sputum, a tenacious biopolymer network accumulating in the airways, critically interferes with the effectiveness of pulmonary gene delivery. To overcome this challenge, nanoparticulate ternary gene-p...
- Combination of chondroitin sulfate and polyplex micelles from Poly(ethylene glycol)-poly{N '-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} block copolymer for prolonged in vivo gene transfection with reduced toxicity
[作者：Uchida, S; Itaka, K; Chen, QX; Osada, K; Miyata, K; Ishii, T; Harada-Shiba, M; Kataoka, K,期刊：Journal of controlled release, 页码：296-302 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2]
- Nonviral polycation-based gene carriers (polyplexes) have attracted attention as safe and efficient gene delivery systems. Polyplex micelles comprised of poly(ethyleneglycol)-block-poly{N'-[N-(2-aminoethyl)-2-aminoethyl]...
- HPMA-oligolysine copolymers for gene delivery: Optimization of peptide length and polymer molecular weight
[作者：Johnson, RN; Chu, DSH; Shi, J; Schellinger, JG; Carlson, PM; Pun, SH,期刊：Journal of controlled release, 页码：303-311 , 文章类型： Article; Proceedings Paper，,卷期：2011年155-2]
- Polycations are one of the most frequently used classes of materials for non-viral gene transfer in vivo. Several studies have demonstrated a sensitive relationship between polymer structure and delivery activity. In thi...
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