- Brain accumulation of sunitinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by oral elacridar and sunitinib coadministration
[作者:Tang, SC; Lagas, JS; Lankheet, NAG; Poller, B; Hillebrand, MJ; Rosing, H; Beijnen, JH; Schinkel, AH,期刊:International Journal of Cancer, 页码:223-233 , 文章类型: Article,,卷期:2012年130-1]
- Sunitinib is an orally active, multitargeted tyrosine kinase inhibitor which has been used for the treatment of metastatic renal cell carcinoma and imatinib-resistant gastrointestinal stromal tumors. We aimed to investig...
- Comparison of visual inspection with acetic acid and cervical cytology to detect high-grade cervical neoplasia among HIV-infected women in India
[作者:Sahasrabuddhe, VV; Bhosale, RA; Kavatkar, AN; Nagwanshi, CA; Joshi, SN; Jenkins, CA; Shepherd, BE; Kelkar, RS; Sahay, S; Risbud, AR; Vermund, SH; Mehendale, SM,期刊:International Journal of Cancer, 页码:234-240 , 文章类型: Article,,卷期:2012年130-1]
- Human immunodeficiency virus (HIV)-infected women in India and other developing country settings are living longer on antiretroviral therapy, yet their risk for human papillomavirus (HPV)-induced cervical cancer remains ...
- Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells
[作者:Kryczek, I; Liu, SL; Roh, M; Vatan, L; Szeliga, W; Wei, S; Banerjee, M; Mao, YJ; Kotarski, J; Wicha, MS; Liu, RC; Zou, WP,期刊:International Journal of Cancer, 页码:29-39 , 文章类型: Article,,卷期:2012年130-1]
- Identification of cancer stem cells is crucial for advancing cancer biology and therapy. Several markers including CD24, CD44, CD117, CD133, the G subfamily of ATP-binding cassette transporters (ABCG), epithelial specifi...
- Endothelin-1 stimulates motility of head and neck squamous carcinoma cells by promoting stromal-epithelial interactions
[作者:Hinsley, EE; Hunt, S; Hunter, KD; Whawell, SA; Lambert, DW,期刊:International Journal of Cancer, 页码:40-47 , 文章类型: Article,,卷期:2012年130-1]
- The invasion and migration of cancer cells is increasingly recognised to be influenced by factors derived from adjacent tumour-associated stroma. The contextual signals regulating stromal-tumour interactions, however, re...
- Monocytes enhance cell proliferation and LMP1 expression of nasal natural killer/T-cell lymphoma cells by cell contact-dependent interaction through membrane-bound IL-15
[作者:Ishii, H; Takahara, M; Nagato, T; Kis, LL; Nagy, N; Kishibe, K; Harabuchi, Y; Klein, E,期刊:International Journal of Cancer, 页码:48-58 , 文章类型: Article,,卷期:2012年130-1]
- Nasal natural killer (NK)/T-cell lymphoma (NNKTL) is an Epstein-Barr virus (EBV)-related malignancy with poor prognosis and has distinct histological features characterized by angiocentric and polymorphous lymphoreticula...
- Cyclooxygenase-2 inhibition causes antiangiogenic effects on tumor endothelial and vascular progenitor cells
[作者:Muraki, C; Ohga, N; Hida, Y; Nishihara, H; Kato, Y; Tsuchiya, K; Matsuda, K; Totsuka, Y; Shindoh, M; Hida, K,期刊:International Journal of Cancer, 页码:59-70 , 文章类型: Article,,卷期:2012年130-1]
- Tumor angiogenesis is necessary for solid tumor progression and metastasis. Cyclooxygenase (COX)-2 is known to play an important role in cancer growth and invasion, and it activates the signaling pathways controlling cel...
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