- Novel effects of CCN3 that may direct the differentiation of chondrocytes
[作者:Janune, D; Kubota, S; Nishida, T; Kawaki, H; Perbal, B; Iida, S; Takigawa, M,期刊:FEBS Letters, 页码:3033-3040 , 文章类型: Article,,卷期:2011年585-19]
- Identification and characterization of local molecules directing the differentiation of chondrocytes to either transient or permanent cartilage are major issues in cartilage biology. Here, we found CCN family protein 3 (...
- Transcriptional repression of the tumor suppressor DRO1 by AIB1
[作者:Ferragud, J; Avivar-Valderas, A; Pla, A; De Las Rivas, J; de Mora, JF,期刊:FEBS Letters, 页码:3041-3046 , 文章类型: Article,,卷期:2011年585-19]
- Using transcriptomic gene expression profiling we found tumor suppressor DRO1 being repressed in AIB1 transgenic mice. In agreement, AIB1 represses DRO1 promoter and its expression levels inversely correlate with DRO1 in...
- NO donor induces Nec-1-inhibitable, but RIP1-independent, necrotic cell death in pancreatic beta-cells
[作者:Tamura, Y; Chiba, Y; Tanioka, T; Shimizu, N; Shinozaki, S; Yamada, M; Kaneki, K; Mori, S; Araki, A; Ito, H; Kaneki, M,期刊:FEBS Letters, 页码:3058-3064 , 文章类型: Article,,卷期:2011年585-19]
- Nitric oxide (NO) has been implicated in pancreatic beta-cell death in the development of diabetes. The mechanisms underlying NO-induced beta-cell death have not been clearly defined. Recently, receptor-interacting prote...
- Differential requirement for nitric oxide in IGF-1-induced anti-apoptotic, anti-oxidant and anti-atherosclerotic effects
[作者:Sukhanov, S; Higashi, Y; Shai, SY; Blackstock, C; Galvez, S; Vaughn, C; Titterington, J; Delafontaine, P,期刊:FEBS Letters, 页码:3065-3072 , 文章类型: Article,,卷期:2011年585-19]
- We have shown previously that insulin like-growth factor I (IGF-1) suppressed atherosclerosis in Apoe (/) mice and activated endothelial nitric oxide (NO) synthase. To determine whether IGF-1-induced atheroprotection dep...
- The structure of helix 89 of 23S rRNA is important for peptidyl transferase function of Escherichia coli ribosome
[作者:Burakovsky, DE; Sergiev, PV; Steblyanko, MA; Konevega, AL; Bogdanov, AA; Dontsova, OA,期刊:FEBS Letters, 页码:3073-3078 , 文章类型: Article,,卷期:2011年585-19]
- Helix 89 of the 23S rRNA connects ribosomal peptidyltransferase center and elongation factor binding site. Secondary structure of helix 89 determined by X-ray structural analysis involves less base pairs then could be dr...
- The endogenous siRNA pathway in Drosophila impacts stress resistance and lifespan by regulating metabolic homeostasis
[作者:Lim, DH; Oh, CT; Lee, L; Hong, JS; Noh, SH; Hwang, S; Kim, S; Han, SJ; Lee, YS,期刊:FEBS Letters, 页码:3079-3085 , 文章类型: Article,,卷期:2011年585-19]
- Small non-coding RNAs regulate gene expression in a sequence-specific manner. In Drosophila, Dicer-2 (Dcr-2) functions in the biogenesis of endogenous small interfering RNAs (endo-siRNAs). We identified 21 distinct prote...
- MiR-483-5p controls angiogenesis in vitro and targets serum response factor
[作者:Qiao, Y; Ma, N; Wang, XD; Hui, Y; Li, FY; Xiang, Y; Zhou, JY; Zou, CX; Jin, JF; Lv, GX; Jin, HB; Gao, X,期刊:FEBS Letters, 页码:3095-3100 , 文章类型: Article,,卷期:2011年585-19]
- Angiogenesis, a key factor in ischemic heart disease, is rapidly initiated in response to hypoxic or ischemic conditions. MicroRNAs (miRNAs) are endogenously expressed small non-coding RNAs that regulate gene expression ...
- Effects of green tea catechins on gramicidin channel function and inferred changes in bilayer properties
[作者:Ingolfsson, HI; Koeppe, RE; Andersen, OS,期刊:FEBS Letters, 页码:3101-3105 , 文章类型: Article,,卷期:2011年585-19]
- Green tea's health benefits have been attributed to its major polyphenols, the catechins: (-)-epigal-locatechin gallate (EGCG), (-)-epicatechin gallate (ECG), (-)-epigallocatechin (EGC), and epicatechin (EC). Catechins (...
- The tumor suppressor p33(ING1b) upregulates p16(INK4a) expression and induces cellular senescence
[作者:Li, N; Li, Q; Cao, XX; Zhao, GY; Xue, LX; Tong, TJ,期刊:FEBS Letters, 页码:3106-3112 , 文章类型: Article,,卷期:2011年585-19]
- ING1 protein is a tumor suppressor which plays significant roles in multiple cellular activities. p47(ING1a) and p33(ING1b) are major splice isoforms of ING1 and their roles in senescence need further investigations. Her...
- Knockdown of aquaporin 3 is involved in intestinal barrier integrity impairment
[作者:Zhang, WJ; Xu, Y; Chen, Z; Xu, ZK; Xu, H,期刊:FEBS Letters, 页码:3113-3119 , 文章类型: Article,,卷期:2011年585-19]
- AQP3 is a water/glycerol transporter expressed at the basolateral membrane of colonic epithelial cells. Although AQPs are expressed in the gastrointestinal tract, their effect on intestinal barrier has not been clear. He...
- Mesd is a general inhibitor of different Wnt ligands in Wnt/LRP signaling and inhibits PC-3 tumor growth in vivo
[作者:Lin, CH; Lu, WY; Zhai, L; Bethea, T; Berry, K; Qu, ZC; Waud, WR; Li, YH,期刊:FEBS Letters, 页码:3120-3125 , 文章类型: Article,,卷期:2011年585-19]
- Mesd is a specialized chaperone for Wnt co-receptor low-density lipoprotein receptor-related protein-5 (LRP5) and LRP6, which contain four beta-propeller/epidermal growth factor modules, named E1 to E4 from N-to C-termin...
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