- beta-Lysine discrimination by lysyl-tRNA synthetase
[作者：Gilreath, MS; Roy, H; Bullwinkle, TJ; Katz, A; Navarre, WW; Ibba, M,期刊：FEBS Letters, 页码：3284-3288 , 文章类型： Article，,卷期：2011年585-20]
- Elongation factor P is modified with (R)-beta-lysine by the lysyl-tRNA synthetase (LysRS) paralog PoxA. PoxA specificity is orthogonal to LysRS, despite their high similarity. To investigate alpha- and beta-lysine recogn...
- Linalool reduces the expression of 3-hydroxy-3-methylglutaryl CoA reductase via sterol regulatory element binding protein-2-and ubiquitin-dependent mechanisms
[作者：Cho, SY; Jun, HJ; Lee, JH; Jia, Y; Kim, KH; Lee, SJ,期刊：FEBS Letters, 页码：3289-3296 , 文章类型： Article，,卷期：2011年585-20]
- We investigated hypocholesterolemic mechanisms of linalool, an aromatic anti-oxidative monoterpene, which is abundant in teas and essential oils. Oral administration of linalool to mice for 6 weeks significantly lowered ...
- Essential role of the metal-ion in the IPM-assisted domain closure of 3-isopropylmalate dehydrogenase
[作者：Graczer, E; Konarev, PV; Szimler, T; Bacso, A; Bodonyi, A; Svergun, DI; Zavodszky, P; Vas, M,期刊：FEBS Letters, 页码：3297-3302 , 文章类型： Article，,卷期：2011年585-20]
- X-ray structures of 3-isopropylmalate dehydrogenase (IPMDH) do not provide sufficient information on the role of the metal-ion in the metal-IPM assisted domain closure. Here solution studies were carried out to test its ...
- MiR-143 enhances adipogenic differentiation of 3T3-L1 cells through targeting the coding region of mouse pleiotrophin
[作者：Yi, C; Xie, WD; Li, F; Lv, Q; He, J; Wu, JB; Gu, DY; Xu, NH; Zhang, Y,期刊：FEBS Letters, 页码：3303-3309 , 文章类型： Article，,卷期：2011年585-20]
- Adipogenic differentiation of preadipocytes is a complex process regulated by various factors including miRNAs and cytokines. MiR-143 is a well known miRNA that enhances adipogenesis. Pleiotrophin (PTN), a heparin-bindin...
- siRNA-mediated knockdown of aryl hydrocarbon receptor nuclear translocator 2 affects hypoxia-inducible factor-1 regulatory signaling and metabolism in human breast cancer cells
[作者：Qin, XY; Wei, FF; Yoshinaga, J; Yonemoto, J; Tanokura, M; Sone, H,期刊：FEBS Letters, 页码：3310-3315 , 文章类型： Article，,卷期：2011年585-20]
- Recent human studies found that the mRNA expression level of aryl-hydrocarbon receptor nuclear translocator 2 (ARNT2) was positively associated with the prognosis of breast cancer. In this study, we used small interferin...
- Thioredoxin stimulates MMP-9 expression, de-regulates the MMP-9/TIMP-1 equilibrium and promotes MMP-9 dependent invasion in human MDA-MB-231 breast cancer cells
[作者：Farina, AR; Cappabianca, L; DeSantis, G; Di Ianni, N; Ruggeri, P; Ragone, M; Merolle, S; Tonissen, KF; Gulino, A; Mackay, AR,期刊：FEBS Letters, 页码：3328-3336 , 文章类型： Article，,卷期：2011年585-20]
- Increased expression of thioredoxin (Trx)-1 and matrix metalloproteinase (MMP)-9 associates with malignant breast cancer progression. Here, we describe a functional relationship between Trx-1 and MMP-9 in promoting MDA-M...
- Biochemical characterization of the very long-chain fatty acid elongase ELOVL7
[作者：Naganuma, T; Sato, Y; Sassa, T; Ohno, Y; Kihara, A,期刊：FEBS Letters, 页码：3337-3341 , 文章类型： Article，,卷期：2011年585-20]
- Very long-chain fatty acids (VLCFAs) have a variety of physiological functions and are related to numerous disorders. The key step of VLCFA elongation is catalyzed by members of the elongase family, ELOVLs. Mammals have ...
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