- Rituximab Selectively Suppresses Specific Islet Antibodies
[作者：Yu, LP; Herold, K; Krause-Steinrauf, H; McGee, PL; Bundy, B; Pugliese, A; Krischer, J; Eisenbarth, GS,期刊：Diabetes, 页码：2560-2565 , 文章类型： Article，,卷期：2011年60-10]
- OBJECTIVE-The Trial Net Study Group evaluated rituximab, a B-cell-depleting monoclonal antibody, for its effect in new-onset patients with type lA diabetes. Rituximab decreased the loss of C-peptide over the first year o...
- Reduced Serum Vitamin D-Binding Protein Levels Are Associated With Type 1 Diabetes
[作者：Blanton, D; Han, Z; Bierschenk, L; Linga-Reddy, MVP; Wang, HJ; Clare-Salzler, M; Haller, M; Schatz, D; Myhr, C; She, JX; Wasserfall, C; Atkinson, M,期刊：Diabetes, 页码：2566-2570 , 文章类型： Article，,卷期：2011年60-10]
- OBJECTIVE-Previous studies have noted a specific association between type 1 diabetes and insufficient levels of vitamin D, as well as polymorphisms within genes related to vitamin D pathways. Here, we examined whether se...
- Donor Islet Endothelial Cells in Pancreatic Islet Revascularization
[作者：Nyqvist, D; Speier, S; Rodriguez-Diaz, R; Molano, RD; Lipovsek, S; Rupnik, M; Dicker, A; Ilegems, E; Zahr-Akrawi, E; Molina, J; Lopez-Cabeza, M; Villate, S; Abdulreda, MH; Ricordi, C; Caicedo, A; Pileggi, A; Berggren, PO,期刊：Diabetes, 页码：2571-2577 , 文章类型： Article，,卷期：2011年60-10]
- OBJECTIVE-Freshly isolated pancreatic islets contain, in contrast to cultured islets, intraislet endothelial cells (ECs), which can contribute to the formation of functional blood vessels after transplantation. We have c...
- Impaired Glucose Tolerance in the Absence of Adenosine A1 Receptor Signaling
[作者：Faulhaber-Walter, R; Jou, W; Mizel, D; Li, LL; Zhang, JD; Kim, SM; Huang, YN; Chen, M; Briggs, JP; Gavrilova, O; Schnermann, JB,期刊：Diabetes, 页码：2578-2587 , 文章类型： Article，,卷期：2011年60-10]
- OBJECTIVE-The role of adenosine (ADO) in the regulation of glucose homeostasis is not clear. In the current study, we used A1-ADO receptor (A1AR)-deficient mice to investigate the role of ADO/A1AR signaling for glucose h...
- Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance Another Paradox in Endurance-Trained Athletes?
[作者：Amati, F; Dube, JJ; Alvarez-Carnero, E; Edreira, MM; Chomentowski, P; Coen, PM; Switzer, GE; Bickel, PE; Stefanovic-Racic, M; Toledo, FGS; Goodpaster, BH,期刊：Diabetes, 页码：2588-2597 , 文章类型： Article，,卷期：2011年60-10]
- OBJECTIVE-Chronic exercise and obesity both increase intra-myocellular triglycerides (IMTGs) despite having opposing effects on insulin sensitivity. We hypothesized that chronically exercise-trained muscle would be chara...
- GLUT2 Accumulation in Enterocyte Apical and Intracellular Membranes A Study in Morbidly Obese Human Subjects and ob/ob and High Fat-Fed Mice
[作者：Ait-Omar, A; Monteiro-Sepulveda, M; Poitou, C; Le Gall, M; Cotillard, A; Gilet, J; Garbin, K; Houllier, A; Chateau, D; Lacombe, A; Veyrie, N; Hugol, D; Tordjman, J; Magnan, C; Serradas, P; Clement, K; Leturque, A; Brot-Laroche, E,期刊：Diabetes, 页码：2598-2607 , 文章类型： Article，,卷期：2011年60-10]
- OBJECTIVE-In healthy rodents, intestinal sugar absorption in response to sugar-rich meals and insulin is regulated by GLUT2 in enterocyte plasma membranes. Loss of insulin action maintains apical GLUT2 location. In human...
- Vascular Dysfunction in Experimental Diabetes Is Improved by Pentaerithrityl Tetranitrate but Not Isosorbide-5-Mononitrate Therapy
[作者：Schuhmacher, S; Oelze, M; Bollmann, F; Kleinert, H; Otto, C; Heeren, T; Steven, S; Hausding, M; Knorr, M; Pautz, A; Reifenberg, K; Schulz, E; Gori, T; Wenzel, P; Munzel, T; Daiber, A,期刊：Diabetes, 页码：2608-2616 , 文章类型： Article，,卷期：2011年60-10]
- OBJECTIVE-Diabetes is associated with vascular oxidative stress, activation of NADPH oxidase, and uncoupling of nitric oxide (NO) synthase (endothelial NO synthase [eNOS]). Pentaerithrityl tetranitrate (PETN) is an organ...
- Anti-inflammatory and Antioxidant Properties of HDLs Are Impaired in Type 2 Diabetes
[作者：Morgantini, C; Natali, A; Boldrini, B; Imaizumi, S; Navab, M; Fogelman, AM; Ferrannini, E; Reddy, ST,期刊：Diabetes, 页码：2617-2623 , 文章类型： Article，,卷期：2011年60-10]
- OBJECTIVE-In mice, 4F, an apolipoprotein A-I mimetic peptide that restores HDL function, prevents diabetes-induced atherosclerosis. We sought to determine whether HDL function is impaired in type 2 diabetic (T2D) patient...
- Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
[作者：Strawbridge, RJ; Dupuis, J; Prokopenko, I; Barker, A; Ahlqvist, E; Rybin, D; Petrie, JR; Travers, ME; Bouatia-Naji, N; Dimas, AS; Nica, A; Wheeler, E; Chen, H; Voight, BF; Taneera, J; Kanoni, S; Peden, JF; Turrini, F; Gustafsson, S; Zabena, C; Almgren, P; Barker, DJP; Barnes, D; Dennison, EM; Eriksson, JG; Eriksson, P; Eury, E; Folkersen, L; Fox, CS; Frayling, TM; Goel, A; Gu, HF; Horikoshi, M; Isomaa, B; Jackson, AU; Jameson, KA; Kajantie, E; Kerr-Conte, J; Kuulasmaa, T; Kuusisto, J; Loos, RJF; Luan, JA; Makrilakis, K; Manning, AK; Martinez-Larrad, MT; Narisu, N; Mannila, MN; Ohrvik, J; Osmond, C; Pascoe, L; Payne, F; Sayer, AA; Sennblad, B; Silveira, A; Stancakova, A; Stirrups, K; Swift, AJ; Syvanen, AC; Tuomi, T; van 't Hooft, FM; Walker, M; Weedon, MN; Xie, WJ; Zethelius, B; Ongen, H; Malarstig, A; Hopewell, JC; Saleheen, D; Chambers, J; Parish, S; Danesh, J; Kooner, J; Ostenson, CG; Lind, L; Cooper, CC; Serrano-Rios, M; Ferrannini, E; Forsen, TJ; Clarke, R; Franzosi, MG; Seedorf, ,期刊：Diabetes, 页码：2624-2634 , 文章类型： Article，,卷期：2011年60-10]
- OBJECTIVE-Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating proinsulin levels are associated with impaired beta-cell function, raised glucose levels, insulin resistance, and type 2 diabetes (T...
- Evidence That HLA Class I and II Associations With Type 1 Diabetes, Autoantibodies to GAD and Autoantibodies to IA-2, Are Distinct
[作者：Howson, JMM; Stevens, H; Smyth, DJ; Walker, NM; Chandler, KA; Bingley, PJ; Todd, JA,期刊：Diabetes, 页码：2635-2644 , 文章类型： Article，,卷期：2011年60-10]
- OBJECTIVE-A major feature of type 1 diabetes is the appearance of islet autoantibodies before diagnosis. However, although the genetics of type 1 diabetes is advanced, the genetics of islet autoantibodies needs further i...
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