- RNA-protein binding interface in the telomerase ribonucleoprotein
[作者:Bley, CJ; Qi, XD; Rand, DP; Borges, CR; Nelson, RW; Chen, JJL,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20333-20338 , 文章类型: Article,,卷期:2011年108-51]
- Telomerase is a specialized reverse transcriptase containing an intrinsic telomerase RNA (TR) which provides the template for telomeric DNA synthesis. Distinct from conventional reverse transcriptases, telomerase has evo...
- Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA
[作者:Zeng, ZX; Min, BS; Huang, J; Hong, K; Yang, YT; Collins, K; Lei, M,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20357-20361 , 文章类型: Article,,卷期:2011年108-51]
- Telomerase copies its internal RNA template to synthesize telomeric DNA repeats. Unlike other polymerases, telomerase can retain its single-stranded product through multiple rounds of template dissociation and reposition...
- Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells
[作者:Coufal, NG; Garcia-Perez, JL; Peng, GE; Marchetto, MCN; Muotri, AR; Mu, YL; Carson, CT; Macia, A; Moran, JV; Gage, FH,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:20382-20387 , 文章类型: Article,,卷期:2011年108-51]
- Long interspersed element-1 (L1) retrotransposons compose similar to 20% of the mammalian genome, and ongoing L1 retrotransposition events can impact genetic diversity by various mechanisms. Previous studies have demonst...
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