- Phosphatase and Tensin Homolog Regulates the Pluripotent State and Lineage Fate Choice in Human Embryonic Stem Cells
[作者:Alva, JA; Lee, GE; Escobar, EE; Pyle, AD,期刊:Stem Cells, 页码:1952-1962 , 文章类型: Article,,卷期:2011年29-12]
- Understanding the intrinsic and extrinsic signals that regulate the molecular basis of the pluripotent state may improve our understanding of mammalian embryogenesis, different states of pluripotency, and our ability to ...
- Two-Phase Analysis of Molecular Pathways Underlying Induced Pluripotent Stem Cell Induction
[作者:Lin, ZY; Perez, P; Lei, DB; Xu, JY; Gao, X; Bao, JX,期刊:Stem Cells, 页码:1963-1974 , 文章类型: Article,,卷期:2011年29-12]
- Induced pluripotent stem cells (iPSCs) can be reprogrammed from adult somatic cells by transduction with Oct4, Sox2, Klf4, and c-Myc, but the molecular cascades initiated by these factors remain poorly understood. Impedi...
- Fibroblast Growth Factor Regulates Human Neuroectoderm Specification Through ERK1/2-PARP-1 Pathway
[作者:Yoo, YD; Huang, CT; Zhang, XQ; Lavaute, TM; Zhang, SC,期刊:Stem Cells, 页码:1975-1982 , 文章类型: Article,,卷期:2011年29-12]
- Fibroblast growth factor (FGF) signaling and PAX6 transcription are required for neuroectoderm specification of human embryonic stem cells (hESCs). In this study, we asked how FGF signaling leads to PAX6 transcription an...
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