- Enhanced Extravasation, Stability and in Vivo Cardiac Gene Silencing via in Situ siRNA-Albumin Conjugation
[作者:Lau, S; Graham, B; Cao, N; Boyd, BJ; Pouton, CW; White, PJ,期刊:Molecular Pharmaceutics, 页码:71-80 , 文章类型: Article,,卷期:2012年9-1]
- A potential barrier to progression of siRNA therapeutics to the clinic is the ability of these agents to cross the vascular endothelium to reach target cells. This study aimed to bypass the endothelial barrier by harness...
- Fabrication of Flocculation-Resistant pH/Ionic Strength/Temperature Multiresponsive Hollow Microspheres and Their Controlled Release
[作者:Mu, B; Liu, P; Li, XR; Du, PC; Dong, Y; Wang, YJ,期刊:Molecular Pharmaceutics, 页码:91-101 , 文章类型: Article,,卷期:2012年9-1]
- pH/ionic strength/temperature multiresponsive hollow microspheres were successfully prepared by the Ce(IV) initiated grafting polymerization of N-isopropylacrylamide (NIPAm) onto the multilayered polyelectrolyte shells e...
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