- Desumoylation of the Endoplasmic Reticulum Membrane VAP Family Protein Scs2 by Ulp1 and SUMO Regulation of the Inositol Synthesis Pathway
[作者:Felberbaum, R; Wilson, NR; Cheng, DM; Peng, JM; Hochstrasser, M,期刊:Molecular and Cellular Biology, 页码:64-75 , 文章类型: Article,,卷期:2012年32-1]
- Posttranslational protein modification by the ubiquitin-like SUMO protein is critical to eukaryotic cell regulation, but much remains unknown regarding its operation and substrates. Here we report that specific mutations...
- Eukaryotic Translation Initiation Factor 3, Subunit a, Regulates the Extracellular Signal-Regulated Kinase Pathway
[作者:Xu, TR; Lu, RF; Romano, D; Pitt, A; Houslay, MD; Milligan, G; Kolch, W,期刊:Molecular and Cellular Biology, 页码:88-95 , 文章类型: Article,,卷期:2012年32-1]
- The extracellular signal-regulated kinase (ERK) pathway participates in the control of numerous cellular processes, including cell proliferation. Since its activation kinetics are critical for to its biological effects, ...
- Loss of Akt1 in Mice Increases Energy Expenditure and Protects against Diet-Induced Obesity
[作者:Wan, M; Easton, RM; Gleason, CE; Monks, BR; Ueki, K; Kahn, CR; Birnbaum, MJ,期刊:Molecular and Cellular Biology, 页码:96-106 , 文章类型: Article,,卷期:2012年32-1]
- Akt is encoded by a gene family for which each isoform serves distinct but overlapping functions. Based on the phenotypes of the germ line gene disruptions, Akt1 has been associated with control of growth, whereas Akt2 h...
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