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  • Evaluation and application of modularly assembled zinc-finger nucleases in zebrafish
    [作者:Zhu, C; Smith, T; McNulty, J; Rayla, AL; Lakshmanan, A; Siekmann, AF; Buffardi, M; Meng, XD; Shin, J; Padmanabhan, A; Cifuentes, D; Giraldez, AJ; Look, AT; Epstein, JA; Lawson, ND; Wolfe, SA,期刊:Development, 页码:4555-4564 , 文章类型: Article,,卷期:2011年138-20]
  • Zinc-finger nucleases (ZFNs) allow targeted gene inactivation in a wide range of model organisms. However, construction of target-specific ZFNs is technically challenging. Here, we evaluate a straightforward modular asse...