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  • Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and "Redoxome''
    [作者:Karisch, R; Fernandez, M; Taylor, P; Virtanen, C; St-Germain, JR; Jin, LL; Harris, IS; Mori, J; Mak, TW; Senis, YA; Ostman, A; Moran, MF; Neel, BG,期刊:Cell, 页码:826-840 , 文章类型: Article,,卷期:2011年146-5]
  • Protein-tyrosine phosphatases (PTPs), along with protein-tyrosine kinases, play key roles in cellular signaling. All Class I PTPs contain an essential active site cysteinyl residue, which executes a nucleophilic attack o...