- Immunomonitoring Results of a Phase II/III Study of Malignant Ascites Patients Treated with the Trifunctional Antibody Catumaxomab (Anti-EpCAM x Anti-CD3)
[作者：Jager, M; Schoberth, A; Ruf, P; Hess, J; Hennig, M; Schmalfeldt, B; Wimberger, P; Strohlein, M; Theissen, B; Heiss, MM; Lindhofer, H,期刊：Cancer research, 页码：24-32 , 文章类型： Article，,卷期：2012年72-1]
- Patients with malignant ascites secondary to primary carcinomas benefit from intraperitoneal therapy with the trifunctional antibody catumaxomab (anti-EpCAM x anti-CD3). Here, we report the analysis of peritoneal fluid s...
- Expression and Function of Survivin in Canine Osteosarcoma
[作者：Shoeneman, JK; Ehrhart, EJ; Eickhoff, JC; Charles, JB; Powers, BE; Thamm, DH,期刊：Cancer research, 页码：249-259 , 文章类型： Article，,卷期：2012年72-1]
- Osteosarcoma has a high mortality rate and remains in need of more effective therapeutic approaches. Survivin is an inhibitor of apoptosis family member protein that blocks apoptosis and drives proliferation in human can...
- Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases
[作者：Li, JX; Malakhova, M; Mottamal, M; Reddy, K; Kurinov, I; Carper, A; Langfald, A; Oi, N; Kim, MO; Zhu, F; Sosa, CP; Zhou, KY; Bode, AM; Dong, ZG,期刊：Cancer research, 页码：260-270 , 文章类型： Article，,卷期：2012年72-1]
- Ultraviolet (UV) irradiation is the leading factor in the development of skin cancer, prompting great interest in chemopreventive agents for this disease. In this study, we report the discovery of norathyriol, a plant-de...
- Genetically Modified T cells Targeting Interleukin-11 Receptor alpha-Chain Kill Human Osteosarcoma Cells and Induce the Regression of Established Osteosarcoma Lung Metastases
[作者：Huang, GX; Yu, L; Cooper, LJN; Hollomon, M; Huls, H; Kleinerman, ES,期刊：Cancer research, 页码：271-281 , 文章类型： Article，,卷期：2012年72-1]
- The treatment of osteosarcoma pulmonary metastases remains a challenge. T cells genetically modified to express a chimeric antigen receptor (CAR), which recognizes a tumor-associated antigen, have shown activity against ...
- Radiosensitization of Human Pancreatic Cancer Cells by MLN4924, an Investigational NEDD8-Activating Enzyme Inhibitor
[作者：Wei, DP; Li, H; Yu, J; Sebolt, JT; Zhao, L; Lawrence, TS; Smith, PG; Morgan, MA; Sun, Y,期刊：Cancer research, 页码：282-293 , 文章类型： Article，,卷期：2012年72-1]
- Radiotherapy is used in locally advanced pancreatic cancers in which it can improve survival in combination with gemcitabine. However, prognosis is still poor in this setting in which more effective therapies remain need...
- Intracellular ATP Levels Are a Pivotal Determinant of Chemoresistance in Colon Cancer Cells
[作者：Zhou, YF; Tozzi, F; Chen, JY; Fan, F; Xia, L; Wang, JR; Gao, G; Zhang, AJ; Xia, XF; Brasher, H; Widger, W; Ellis, LM; Zhang, WH,期刊：Cancer research, 页码：304-314 , 文章类型： Article，,卷期：2012年72-1]
- Altered metabolism in cancer cells is suspected to contribute to chemoresistance, but the precise mechanisms are unclear. Here, we show that intracellular ATP levels are a core determinant in the development of acquired ...
- EZH2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor Genes CASZ1, CLU, RUNX3, and NGFR
[作者：Wang, CX; Liu, ZH; Woo, CW; Li, ZJ; Wang, LF; Wei, JS; Marquez, VE; Bates, SE; Jin, QH; Khan, J; Ge, K; Thiele, CJ,期刊：Cancer research, 页码：315-324 , 文章类型： Article，,卷期：2012年72-1]
- Neuroblastoma (NB) is the most common extracranial pediatric solid tumor with an undifferentiated status and generally poor prognosis, but the basis for these characteristics remains unknown. In this study, we show that ...
- The White Adipose Tissue Used in Lipotransfer Procedures Is a Rich Reservoir of CD34(+) Progenitors Able to Promote Cancer Progression
[作者：Martin-Padura, I; Gregato, G; Marighetti, P; Mancuso, P; Calleri, A; Corsini, C; Pruneri, G; Manzotti, M; Lohsiriwat, V; Rietjens, M; Petit, JY; Bertolini, F,期刊：Cancer research, 页码：325-334 , 文章类型： Article，,卷期：2012年72-1]
- Previous studies have suggested a "catalytic role" in neoplastic angiogenesis and cancer progression for bone marrow-derived endothelial progenitor cells (EPC). However, preclinical and clinical studies have shown that t...
- A Novel Method of Transcriptional Response Analysis to Facilitate Drug Repositioning for Cancer Therapy
[作者：Jin, GX; Fu, CH; Zhao, H; Cui, KM; Chang, J; Wong, STC,期刊：Cancer research, 页码：33-44 , 文章类型： Article，,卷期：2012年72-1]
- Little research has been done to address the huge opportunities that may exist to reposition existing approved or generic drugs for alternate uses in cancer therapy. In addition, there has been little work on strategies ...
- Curcumin Analogue CDF Inhibits Pancreatic Tumor Growth by Switching on Suppressor microRNAs and Attenuating EZH2 Expression
[作者：Bao, B; Ali, S; Banerjee, S; Wang, ZW; Logna, F; Azmi, AS; Kong, DJ; Ahmad, A; Li, YW; Padhye, S; Sarkar, FH,期刊：Cancer research, 页码：335-345 , 文章类型： Article，,卷期：2012年72-1]
- The histone methyltransferase EZH2 is a central epigenetic regulator of cell survival, proliferation, and cancer stem cell (CSC) function. EZH2 expression is increased in various human cancers, including highly aggressiv...
- Mesenchymal Stromal Cell Mutations and Wound Healing Contribute to the Etiology of Desmoid Tumors
[作者：Carothers, AM; Rizvi, H; Hasson, RM; Heit, YI; Davids, JS; Bertagnolli, MM; Cho, NL,期刊：Cancer research, 页码：346-355 , 文章类型： Article，,卷期：2012年72-1]
- Desmoid tumors are nonmalignant neoplasms of mesenchymal origin that mainly contain fibroblast lineage cells. These tumors often occur in patients with familial adenomatous polyposis (FAP) coli who have germ line mutatio...
- Metabolomic NMR Fingerprinting to Identify and Predict Survival of Patients with Metastatic Colorectal Cancer
[作者：Bertini, I; Cacciatore, S; Jensen, BV; Schou, JV; Johansen, JS; Kruhoffer, M; Luchinat, C; Nielsen, DL; Turano, P,期刊：Cancer research, 页码：356-364 , 文章类型： Article，,卷期：2012年72-1]
- Earlier detection of patients with metastatic colorectal cancer (mCRC) might improve their treatment and survival outcomes. In this study, we used proton nuclear magnetic resonance ((1)H-NMR) to profile the serum metabol...
- ERK1/2 Regulation of CD44 Modulates Oral Cancer Aggressiveness
[作者：Judd, NP; Winkler, AE; Murillo-Sauca, O; Brotman, JJ; Law, JH; Lewis, JS; Dunn, GP; Bui, JD; Sunwoo, JB; Uppaluri, R,期刊：Cancer research, 页码：365-374 , 文章类型： Article，,卷期：2012年72-1]
- Carcinogen-induced oral cavity squamous cell carcinoma (OSCC) incurs significant morbidity and mortality and constitutes a global health challenge. To gain further insight into this disease, we generated cell line models...
- Defective NF-kappa B Signaling in Metastatic Head and Neck Cancer Cells Leads to Enhanced Apoptosis by Double-Stranded RNA
[作者：Umemura, N; Zhu, JZ; Mburu, YK; Forero, A; Hsieh, PN; Muthuswamy, R; Kalinski, P; Ferris, RL; Sarkar, SN,期刊：Cancer research, 页码：45-55 , 文章类型： Article，,卷期：2012年72-1]
- Ligands to several Toll-like receptors (TLR), which mediate innate immune responses and chronic inflammation have been used as adjuvants to immunotherapy to enhance their antitumor activity. In particular, double-strande...
|