- HLA mismatch direction in cord blood transplantation: impact on outcome and implications for cord blood unit selection
[作者:Stevens, CE; Carrier, C; Carpenter, C; Sung, D; Scaradavou, A,期刊:Blood, 页码:3969-3978 , 文章类型: Article,,卷期:2011年118-14]
- Donor-recipient human leukocyte antigen mismatch level affects the outcome of unrelated cord blood (CB) transplantation. To identify possible "permissive" mismatches, we examined the relationship between direction of hum...
- Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane
[作者:Bignon, M; Pichol-Thievend, C; Hardouin, J; Malbouyres, M; Brechot, N; Nasciutti, L; Barret, A; Teillon, J; Guillon, E; Etienne, E; Caron, M; Joubert-Caron, R; Monnot, C; Ruggiero, F; Muller, L; Germain, S,期刊:Blood, 页码:3979-3989 , 文章类型: Article,,卷期:2011年118-14]
- Sprouting angiogenesis is associated with extensive extracellular matrix (ECM) remodeling. The molecular mechanisms involved in building the vascular microenvironment and its impact on capillary formation remain elusive....
- ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters
[作者:Huang, RL; Teo, ZQ; Chong, HC; Zhu, PC; Tan, MJ; Tan, CK; Lam, CRI; Sng, MK; Leong, DTW; Tan, SM; Kersten, S; Ding, JL; Li, HY; Tan, NS,期刊:Blood, 页码:3990-4002 , 文章类型: Article,,卷期:2011年118-14]
- Vascular disruption induced by interactions between tumor-secreted permeability factors and adhesive proteins on endothelial cells facilitates metastasis. The role of tumor-secreted C-terminal fibrinogen-like domain of a...
- Vascular endothelial growth factor-induced elimination of the type 1 interferon receptor is required for efficient angiogenesis
[作者:Zheng, H; Qian, J; Carbone, CJ; Leu, NA; Baker, DP; Fuchs, SY,期刊:Blood, 页码:4003-4006 , 文章类型: Article,,卷期:2011年118-14]
- Angiogenesis is stimulated by vascular endothelial growth factor (VEGF) and antagonized by type 1 interferons, including IFN-alpha/beta. On engaging their respective receptors (VEGFR2 and IFNAR), both stimuli activate pr...
- Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes
[作者:Rowley, JW; Oler, AJ; Tolley, ND; Hunter, BN; Low, EN; Nix, DA; Yost, CC; Zimmerman, GA; Weyrich, AS,期刊:Blood, 页码:E101-E111 , 文章类型: Article,,卷期:2011年118-14]
- Inbred mice are a useful tool for studying the in vivo functions of platelets. Nonetheless, the mRNA signature of mouse platelets is not known. Here, we use paired-end next-generation RNA sequencing (RNA-seq) to characte...
- A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with del5q
[作者:Fenaux, P; Giagounidis, A; Selleslag, D; Beyne-Rauzy, O; Mufti, G; Mittelman, M; Muus, P; Boekhorst, PT; Sanz, G; del Canizo, C; Guerci-Bresler, A; Nilsson, L; Platzbecker, U; Lubbert, M; Quesnel, B; Cazzola, M; Ganser, A; Bowen, D; Schlegelberger, B; Aul, C; Knight, R; Francis, J; Fu, T; Hellstrom-Lindberg, E,期刊:Blood, 页码:3765-3776 , 文章类型: Article,,卷期:2011年118-14]
- This phase 3, randomized, double-blind study assessed the efficacy and safety of lenalidomide in 205 red blood cell (RBC) transfusion-dependent patients with International Prognostic Scoring System Low-/Intermediate-1-ri...
- Pathogenesis and treatment of xanthomatosis associated with monoclonal gammopathy
[作者:Szalat, R; Arnulf, B; Karlin, L; Rybojad, M; Asli, B; Malphettes, M; Galicier, L; Vignon-Pennamen, MD; Harel, S; Cordoliani, F; Fuzibet, JG; Oksenhendler, E; Clauvel, JP; Brouet, JC; Fermand, JP,期刊:Blood, 页码:3777-3784 , 文章类型: Review,,卷期:2011年118-14]
- Xanthomas are a common manifestation of lipid metabolism disorders. They include hyperlipemic xanthoma, normolipemic xanthoma, and a related condition, necrobiotic xanthogranuloma (NXG). All 3 forms can be associated wit...
- How I treat extramedullary acute myeloid leukemia
[作者:Bakst, RL; Tallman, MS; Douer, D; Yahalom, J,期刊:Blood, 页码:3785-3793 , 文章类型: Article,,卷期:2011年118-14]
- Extramedullary (EM) manifestations of acute leukemia include a wide variety of clinically significant phenomena that often pose therapeutic dilemmas. Myeloid sarcoma (MS) and leukemia cutis (LC) represent 2 well-known EM...
- Risk factors and mortality associated with an elevated tricuspid regurgitant jet velocity measured by Doppler-echocardiography in thalassemia: a Thalassemia Clinical Research Network report
[作者:Morris, CR; Kim, HY; Trachtenberg, F; Wood, J; Quinn, CT; Sweeters, N; Kwiatkowski, JL; Thompson, AA; Giardina, PJ; Boudreaux, J; Olivieri, NF; Porter, JB; Neufeld, EJ; Vichinsky, EP,期刊:Blood, 页码:3794-3802 , 文章类型: Article,,卷期:2011年118-14]
- An elevated tricuspid regurgitant jet velocity (TRV) is associated with hemolysis and early mortality in sickle cell disease, yet risk factors, clinical parameters, and mortality associated with this biomarker in thalass...
- TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics
[作者:Chou, WC; Chou, SC; Liu, CY; Chen, CY; Hou, HA; Kuo, YY; Lee, MC; Ko, BS; Tang, JL; Yao, M; Tsay, W; Wu, SJ; Huang, SY; Hsu, SC; Chen, YC; Chang, YC; Kuo, YY; Kuo, KT; Lee, FY; Liu, MC; Liu, CW; Tseng, MH; Huang, CF; Tien, HF,期刊:Blood, 页码:3803-3810 , 文章类型: Article,,卷期:2011年118-14]
- The studies concerning clinical implications of TET2 mutation in patients with primary acute myeloid leukemia (AML) are scarce. We analyzed TET2 mutation in 486 adult patients with primary AML. TET2 mutation occurred in ...
- Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand
[作者:Jain, A; Kovacs, JA; Nelson, DL; Migueles, SA; Pittaluga, S; Fanslow, W; Fan, XY; Wong, DW; Massey, J; Hornung, R; Brown, MR; Spinner, JJ; Liu, SY; Davey, V; Hill, HA; Ochs, H; Fleisher, TA,期刊:Blood, 页码:3811-3817 , 文章类型: Article,,卷期:2011年118-14]
- X-linked hyper IgM syndrome (XHM) is a combined immune deficiency disorder caused by genetic alterations in CD40 ligand. The purpose of this study was to investigate the safety and efficacy of recombinant CD40 ligand (rC...
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