- Cytochrome C(552) from Thermus thermophilus Engineered for Facile Substitution of Prosthetic Group
[作者:Ibrahim, SM; Nakajima, H; Ohta, T; Ramanathan, K; Takatani, N; Naruta, Y; Watanabe, Y,期刊:Biochemistry, 页码:9826-9835 , 文章类型: Article,,卷期:2011年50-45]
- The facile replacement of heme c in cytochromes c with non-natural prosthetic groups has been difficult to achieve due to two thioether linkages between cysteine residues and the heme. Fee et al. demonstrated that cytoch...
- The GRP1 PH Domain, Like the AKT1 PH Domain, Possesses a Sentry Glutamate Residue Essential for Specific Targeting to Plasma Membrane PI(3,4,5)P(3)
[作者:Pilling, C; Landgraf, KE; Falke, JJ,期刊:Biochemistry, 页码:9845-9856 , 文章类型: Article,,卷期:2011年50-45]
- During the appearance of the signaling lipid PI(3,4,5)P(3), an important subset of pleckstrin homology (PH) domains target signaling proteins to the plasma membrane. To ensure proper pathway regulation, such PI(3,4,5)P(3...
- Identification of Key Residues Involved in the Dimerization of the Secretory Na(+)-K(+)-2Cl(-) Cotransporter NKCC1
[作者:Parvin, MN; Turner, RJ,期刊:Biochemistry, 页码:9857-9864 , 文章类型: Article,,卷期:2011年50-45]
- The "secretory" Na(+)-K(+)-2Cl(-) cotransporter, NKCC1, belongs to the SLC12 gene family of electroneutral cation-chloride cotransporters. A number of these proteins, including NKCC1 itself, exist as homodimers in the me...
- Characterization of the Side-Chain Hydroxyl Moieties of Residues Y56, Y111, Y238, Y338, and S339 as Determinants of Specificity in E. coli Cystathionine beta-Lyase
[作者:Lodha, PH; Aitken, SM,期刊:Biochemistry, 页码:9876-9885 , 文章类型: Article,,卷期:2011年50-45]
- Cystathionine beta-lyase (CBL) catalyzes the hydrolysis of L-cystathionine (L-Cth) to produce L-homocysteine, pyruvate, and ammonia. A series of site-directed variants of Escherichia coli CBL (eCBL) was constructed to in...
- Allosteric Interaction of Nucleotides and tRNA(ala) with E. coli Alanyl-tRNA Synthetase
[作者:Dignam, JD; Guo, JS; Griffith, WP; Garbett, NC; Holloway, A; Mueser, T,期刊:Biochemistry, 页码:9886-9900 , 文章类型: Article,,卷期:2011年50-45]
- Alanyl-tRNA synthetase, a dimeric class 2 aminoacyl-tRNA synthetase, activates glycine and serine at significant rates. An editing activity hydrolyzes Gly-tRNA(ala) and Ser-tRNA(ala) to ensure fidelity of aminoacylation....
- The Crystal Structure of Necrosis- and Ethylene-Inducing Protein 2 from the Causal Agent of Cacao's Witches' Broom Disease Reveals Key Elements for Its Activity
[作者:Zaparoli, G; Barsottini, MRD; de Oliveira, JF; Dyszy, F; Teixeira, PJPL; Barau, JG; Garcia, O; Costa, AJ; Ambrosio, ALB; Pereira, GAG; Dias, SMG,期刊:Biochemistry, 页码:9901-9910 , 文章类型: Article,,卷期:2011年50-45]
- The necrosis- and ethylene-inducing peptide 1 (NEP1)-like proteins (NLPs) are proteins secreted from bacteria, fungi and oomycetes, triggering immune responses and cell death in dicotyledonous plants. Genomic-scale studi...
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