- Sigma-1Rs are upregulated via PERK/eIF2 alpha/ATF4 pathway and execute protective function in ER stress
[作者:Mitsuda, T; Omi, T; Tanimukai, H; Sakagami, Y; Tagami, S; Okochi, M; Kudo, T; Takeda, M,期刊:Biochemical and Biophysical Research Communications, 页码:519-525 , 文章类型: Article,,卷期:2011年415-3]
- Sigma-1 receptors (Sig-1Rs) are the ER resident proteins. Sig-1Rs in the brain have been reported to be significantly reduced in patients with schizophrenia. The impediment of regulating Sig-1Rs expression levels increas...
- Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-beta production
[作者:Hasegawa, H; Lei, J; Matsumoto, T; Onishi, S; Suemori, K; Yasukawa, M,期刊:Biochemical and Biophysical Research Communications, 页码:526-531 , 文章类型: Article,,卷期:2011年415-3]
- Naturally occurring CD4(+)CD25(+) regulatory T cells (nTregs) play a pivotal role in the maintenance of self-tolerance and immune homeostasis. To gain insight into the mechanism of action of nTregs in pathological and ph...
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