- Regulation of macrophage differentiation and polarization by group IVC phospholipase A(2)
[作者:Ishihara, K; Kuroda, A; Sugihara, K; Kanai, S; Nabe, T; Akiba, S,期刊:Biochemical and Biophysical Research Communications, 页码:325-330 , 文章类型: Article,,卷期:2011年416-3-4]
- Although the cellular function of group IVC phospholipase A(2) (IVC-PLA(2)) remains to be understood, the expression of IVC-PLA(2) in human monocytic THP-1 cells was increased during phorbol ester-induced macrophage diff...
- Extracellular low pH affects circadian rhythm expression in human primary fibroblasts
[作者:Lee, SK; Achieng, E; Maddox, C; Chen, SC; Iuvone, PM; Fukuhara, C,期刊:Biochemical and Biophysical Research Communications, 页码:337-342 , 文章类型: Article,,卷期:2011年416-3-4]
- Circadian rhythm is a fundamental biological system involved in the regulation of various physiological functions. However, little is known about a nature or function of circadian clock in human primary cells. In the pre...
- 3D structure and immunogenicity of Plasmodium falciparum sporozoite induced associated protein peptides as components of fully-protective anti-malarial vaccine
[作者:Alba, MP; Almonacid, H; Calderon, D; Chacon, EA; Poloche, LA; Patarroyo, MA; Patarroyo, ME,期刊:Biochemical and Biophysical Research Communications, 页码:349-355 , 文章类型: Article,,卷期:2011年416-3-4]
- SIAP-1 and SIAP-2 are proteins which are implicated in early events involving Plasmodium falciparum infection of the Anopheles mosquito vector and the human host. High affinity HeLa and HepG2 cell binding conserved pepti...
- Endoplasmic reticulum stress enhances gamma-secretase activity
[作者:Ohta, K; Mizuno, A; Li, SM; Itoh, M; Ueda, M; Ohta, E; Hida, Y; Wang, MX; Furoi, M; Tsuzuki, Y; Sobajima, M; Bohmoto, Y; Fukushima, T; Kobori, M; Inuzuka, T; Nakagawa, T,期刊:Biochemical and Biophysical Research Communications, 页码:362-366 , 文章类型: Article,,卷期:2011年416-3-4]
- The endoplasmic reticulum (ER) copes with unfolded proteins in the lumen (ER stress) by activating three distinct intracellular signaling pathways of unfolded protein response (UPR). ER stress contributes to the pathogen...
- Histone demethylase JMJD2B is required for tumor cell proliferation and survival and is overexpressed in gastric cancer
[作者:Li, WJ; Zhao, L; Zang, W; Liu, ZF; Chen, L; Liu, TT; Xu, DW; Jia, JH,期刊:Biochemical and Biophysical Research Communications, 页码:372-378 , 文章类型: Article,,卷期:2011年416-3-4]
- Epigenetic alterations such as aberrant expression of histone-modifying enzymes have been implicated in tumorigenesis. Jumonji domain containing 2B (JMJD2B) is a newly identified histone demethylase that regulates chroma...
- The X protein of hepatitis B virus activates hepatoma cell proliferation through repressing melanoma inhibitory activity 2 gene
[作者:Xu, YL; Yang, Y; Cai, YY; Liu, F; Liu, YL; Zhu, Y; Wu, JG,期刊:Biochemical and Biophysical Research Communications, 页码:379-384 , 文章类型: Article,,卷期:2011年416-3-4]
- Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer deaths globally. Chronic hepatitis B virus (HBV) infection accounts for over 75% of all HCC cases; however, the molecular pathogenesis of HCC is not we...
- XLG alpha(olf) regulates expression of p27(Kip1) in a CSN5 and CDK2 dependent manner
[作者:Akita, K; Takahashi, Y; Takata, N; Hashimoto, M; Kataoka, M; Tomigahara, Y; Saito, K,期刊:Biochemical and Biophysical Research Communications, 页码:385-390 , 文章类型: Article,,卷期:2011年416-3-4]
- XLG alpha(olf) is an extra large transcriptional variant of the heterotrimeric G protein, G alpha(olf), which we previously reported to be localized in the Golgi apparatus and interacted with Rab3A and Rab8A through its ...
- Prolonged effect of fluid flow stress on the proliferative activity of mesothelial cells after abrupt discontinuation of fluid streaming
[作者:Aoki, S; Ikeda, S; Takezawa, T; Kishi, T; Makino, J; Uchihashi, K; Matsunobu, A; Noguchi, M; Sugihara, H; Toda, S,期刊:Biochemical and Biophysical Research Communications, 页码:391-396 , 文章类型: Article,,卷期:2011年416-3-4]
- Encapsulating peritoneal sclerosis (EPS) often develops after transfer to hemodialysis and transplantation. Both termination of peritoneal dialysis (PD) and transplantation-related factors are risks implicated in post-PD...
- Synthetic cyclohexenyl chalcone natural products possess cytotoxic activities against prostate cancer cells and inhibit cysteine cathepsins in vitro
[作者:Majumdar, ID; Devanabanda, A; Fox, B; Schwartzman, J; Cong, H; Porco, JA; Weber, HC,期刊:Biochemical and Biophysical Research Communications, 页码:397-402 , 文章类型: Article,,卷期:2011年416-3-4]
- A number of cyclohexenyl chalcone Diels-Alder natural products possess promising biological properties including strong cytotoxicity in various human cancer cells. Herein, we show that natural products in this class incl...
- Overexpression of the human ubiquitin E3 ligase CUL4A alleviates hypoxia-reoxygenation injury in pheochromocytoma (PC12) cells
[作者:Tan, C; Zhang, LY; Chen, H; Xiao, L; Liu, XP; Zhang, JX,期刊:Biochemical and Biophysical Research Communications, 页码:403-408 , 文章类型: Article,,卷期:2011年416-3-4]
- The ubiquitin E3 ligase CUL4A plays important roles in diverse cellular processes including carcinogenesis and proliferation. It has been reported that the expression of CUL4A can be induced by hypoxic-ischemic injury. H...
- Negative-feedback regulation of ATP release: ATP release from cardiomyocytes is strictly regulated during ischemia
[作者:Kunugi, S; Iwabuchi, S; Matsuyama, D; Okajima, T; Kawahara, K,期刊:Biochemical and Biophysical Research Communications, 页码:409-415 , 文章类型: Article,,卷期:2011年416-3-4]
- Extracellular ATP acts as a potent agonist on cardiomyocytes, inducing a broad range of physiological responses via P2 purinoceptors. Its concentration in the interstitial space within the heart is elevated during ischem...
- The human Ino80 binds to microtubule via the E-hook of tubulin: Implications for the role in spindle assembly
[作者:Park, EJ; Hur, SK; Lee, HS; Lee, SA; Kwon, J,期刊:Biochemical and Biophysical Research Communications, 页码:416-420 , 文章类型: Article,,卷期:2011年416-3-4]
- The human INO80 chromatin remodeling complex, comprising the Ino80 ATPase (hIno80) and the associated proteins such as Tip49a, has been implicated in a variety of nuclear processes other than transcription. We previously...
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