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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共48条记录   Class II-Associated Invariant Chain Peptide Expression Represents a Novel Parameter for Flow Cytometric Detection of Acute Promyelocytic Leukemia [作者：van Luijn, MM; Westers, TM; Chamuleau, MED; van Ham, SM; Ossenkoppele, GJ; van de Loosdrecht, AA,期刊：American Journal of Pathology, 页码：2157-2161 , 文章类型： Article，,卷期：2011年179-5] Because of severe bleeding complications, patients with acute promyelocytic leukemia (APL) have to be treated with all-trans retinoic acid immediately following diagnosis. In addition to morphology, flow cytometry contri... miR-193b Regulates Mcl-1 in Melanoma [作者：Chen, JM; Zhang, X; Lentz, C; Abi-Daoud, M; Pare, GC; Yang, XL; Feilotter, HE; Tron, VA,期刊：American Journal of Pathology, 页码：2162-2168 , 文章类型： Article，,卷期：2011年179-5] MicroRNAs play important roles in gene regulation, and their expression is frequently dysregulated in cancer cells. In a previous study, we reported that miR-193b represses cell proliferation and regulates cyclin D1 in m... High-Resolution Imaging and Antitumor Effects of GFP(+) Bone Marrow-Derived Cells Homing to Syngeneic Mouse Colon Tumors [作者：Finnberg, NK; Hart, LS; Dolloff, NG; Rodgers, ZB; Dicker, DT; El-Deiry, WS,期刊：American Journal of Pathology, 页码：2169-2176 , 文章类型： Article，,卷期：2011年179-5] Bone marrow-derived cells (BMDCs) participate in the growth and spread of tumors of the breast, brain, lung, and stomach. To date, there are limited reports of bone marrow involvement in colon cancer pathogenesis, but su... Tubular Deficiency of von Hippel-Lindau Attenuates Renal Disease Progression in Anti-GBM Glomerulonephritis [作者：Theilig, F; Enke, AK; Scolari, B; Polzin, D; Bachmann, S; Koesters, R,期刊：American Journal of Pathology, 页码：2177-2188 , 文章类型： Article，,卷期：2011年179-5] In many kidney diseases, the original insult primarily involves the glomerulus and may then pass onto the tubulointerstitium. Several hypotheses link glomerular disease to tubular injury; perhaps the foremost hypothesis ... Type I Collagen Cleavage Is Essential for Effective Fibrotic Repair after Myocardial Infarction [作者：Nong, ZX; O'Neil, C; Lei, M; Gros, R; Watson, A; Rizkalla, A; Mequanint, K; Li, SH; Frontini, MJ; Feng, QP; Pickering, JG,期刊：American Journal of Pathology, 页码：2189-2198 , 文章类型： Article，,卷期：2011年179-5] Efficient deposition of type I collagen is fundamental to healing after myocardial infarction. Whether there is also a role for cleavage of type I collagen in infarct healing is unknown. To test this, we undertook corona... Egr-1 Expression During Neointimal Development in Flow-Associated Pulmonary Hypertension [作者：Dickinson, MG; Bartelds, B; Molema, G; Borgdorff, MA; Boersma, B; Takens, J; Weij, M; Wichers, P; Sietsma, H; Berger, RMF,期刊：American Journal of Pathology, 页码：2199-2209 , 文章类型： Article，,卷期：2011年179-5] In flow-associated pulmonary arterial hypertension (PAH), increased pulmonary blood flow is an essential trigger for neointimal formation. Using microarray analysis, we recently found that the early growth response prote... Acid Sphingomyelinase Gene Deficiency Ameliorates the Hyperhomocysteinemia-Induced Glomerular Injury in Mice [作者：Boini, KM; Xia, M; Li, CX; Zhang, C; Payne, LP; Abais, JM; Poklis, JL; Hylemon, PB; Li, PL,期刊：American Journal of Pathology, 页码：2210-2219 , 文章类型： Article，,卷期：2011年179-5] Hyperhomocysteinemia (hHcys) enhances ceramide production, leading to the activation of NADPH oxidase and consequent glomerular oxidative stress and sclerosis. The present study was performed to determine whether acid sp... Impact of Fibroblast Growth Factor-Binding Protein-1 Expression on Angiogenesis and Wound Healing [作者：Tassi, E; McDonnell, K; Gibby, KA; Tilan, JU; Kim, SE; Kodack, DP; Schmidt, MO; Sharif, GM; Wilcox, CS; Welch, WJ; Gallicano, GI; Johnson, MD; Riegel, AT; Wellstein, A,期刊：American Journal of Pathology, 页码：2220-2232 , 文章类型： Article，,卷期：2011年179-5] Fibroblast growth factors (FGFs) participate in embryonic development, in maintenance of tissue homeostasis in the adult, and in various diseases. FGF-binding proteins (FGFBP) are secreted proteins that chaperone FGFs st... Protease Activated Receptor-2 Mediates Activated Protein C-Induced Cutaneous Wound Healing via Inhibition of p38 [作者：Julovi, SM; Xue, ML; Dervish, S; Sambrook, PN; March, L; Jackson, CJ,期刊：American Journal of Pathology, 页码：2233-2242 , 文章类型： Article，,卷期：2011年179-5] Activated protein C (APC) is a natural anticoagulant that exerts anti-inflammatory and cytoprotective properties mediated through the protease activated receptor (PAR)-1. APC can also proteolytically cleave PAR-2, althou... Dendritic Cell-Epithelium Interplay Is a Determinant Factor for Corneal Epithelial Wound Repair [作者：Gao, N; Yin, J; Yoon, GS; Mi, QS; Yu, FSX,期刊：American Journal of Pathology, 页码：2243-2253 , 文章类型： Article，,卷期：2011年179-5] The functions of intraepithelial dendritic cells (DCs) are critical for mucosal innate and adaptive immunity, but little is known about the role of tissue-specific DCs in epithelial homeostasis and tissue repair. By usin... Phosphorylation of Podocalyxin (Ser415) Prevents RhoA and Ezrin Activation and Disrupts Its Interaction with the Actin Cytoskeleton [作者：Fukasawa, H; Obayashi, H; Schmieder, S; Lee, J; Ghosh, P; Farquhar, MG,期刊：American Journal of Pathology, 页码：2254-2265 , 文章类型： Article，,卷期：2011年179-5] Podocalyxin (PC) is a polysialylated, anti-adhesin that is essential for maintaining foot process architecture and the integrity of the glomerular filtration barrier. We showed previously that PC is firmly attached to th... VEGFR-1 Mediates Endothelial Differentiation and Formation of Blood Vessels in a Murine Model of Infantile Hemangioma [作者：Boscolo, E; Mulliken, JB; Bischoff, J,期刊：American Journal of Pathology, 页码：2266-2277 , 文章类型： Article，,卷期：2011年179-5] Vascular endothelial growth factor receptor-1 (VEGFR-1) is a member of the VEGFR family, and binds to VEGF-A, VEGF-B, and placental growth factor. VEGFR-1 contributes to tumor growth and metastasis, but its role in the p... Protease-Activated Receptor 1 and Hematopoietic Cell Tissue Factor Are Required for Hepatic Steatosis in Mice Fed a Western Diet [作者：Kassel, KM; Owens, AP; Rockwell, CE; Sullivan, BP; Wang, RP; Tawfik, O; Li, GD; Guo, GL; Mackman, N; Luyendyk, JP,期刊：American Journal of Pathology, 页码：2278-2289 , 文章类型： Article，,卷期：2011年179-5] Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of obesity and metabolic syndrome and contributes to increased risk of cardiovascular disease and liver-related morbidity and mortality. Indeed, obese... Endogenous Prion Protein Attenuates Experimentally Induced Colitis [作者：Martin, GR; Keenan, CM; Sharkey, KA; Jirik, FR,期刊：American Journal of Pathology, 页码：2290-2301 , 文章类型： Article，,卷期：2011年179-5] Although the cellular prion protein (PrP(C)) is expressed in the enteric nervous system and lamina propria, its function(s) in the gut is unknown. Because PrP(C) may exert a cytoprotective effect in response to various p... CCR3 Blockade Attenuates Eosinophilic Ileitis and Associated Remodeling [作者：Masterson, JC; McNamee, EN; Jedlicka, P; Fillon, S; Ruybal, J; Hosford, L; Rivera-Nieves, J; Lee, JJ; Furuta, GT,期刊：American Journal of Pathology, 页码：2302-2314 , 文章类型： Article，,卷期：2011年179-5] Intestinal remodeling and stricture formation is a complication of inflammatory bowel disease (IBD) that often requires surgical intervention. Although eosinphils are associated with mucosal remodeling in other organs an... mdx(5cv) Mice Manifest More Severe Muscle Dysfunction and Diaphragm Force Deficits than Do mdx Mice [作者：Beastrom, N; Lu, HY; Macke, A; Canan, BD; Johnson, EK; Penton, CM; Kaspar, BK; Rodino-Klapac, LR; Zhou, L; Janssen, PML; Montanaro, F,期刊：American Journal of Pathology, 页码：2464-2474 , 文章类型： Article，,卷期：2011年179-5] Duchenne muscular dystrophy (DMD) is characterized by progressive skeletal muscle dysfunction leading to premature death by the third decade of life. The mdx mouse, the most widely used animal model of DMD, has been extr...