- Butein, a tetrahydroxychalcone, suppresses cancer-induced osteoclastogenesis through inhibition of receptor activator of nuclear factor-kappaB ligand signaling
[作者:Sung, B; Cho, SG; Liu, MY; Aggarwal, BB,期刊:International Journal of Cancer, 页码:2062-2072 , 文章类型: Article,,卷期:2011年129-9]
- Osteoclastogenesis is associated with aging and various age-related inflammatory chronic diseases, including cancer. Receptor activator of nuclear factor-kappaB (NF-kappa B) ligand (RANKL), a member of the tumor necrosis...
- Folic acid supplementation during early hepatocarcinogenesis: cellular and molecular effects
[作者:Chagas, CEA; Bassoli, BK; de Souza, CAS; Deminice, R; Jordao, AA; Paiva, SAR; Dagli, MLZ; Ong, TP; Moreno, FS,期刊:International Journal of Cancer, 页码:2073-2082 , 文章类型: Article,,卷期:2011年129-9]
- Folic acid (FA) supplementation during carcinogenesis is controversial. Considering the impact of liver cancer as a public health problem and mandatory FA fortification in several countries, the role of FA supplementatio...
- Bcl-2 promotes malignant progression in a PDGF-B-dependent murine model of oligodendroglioma
[作者:Doucette, T; Yang, YH; Zhang, W; Fuller, GN; Suki, D; Fults, DW; Rao, G,期刊:International Journal of Cancer, 页码:2093-2103 , 文章类型: Article,,卷期:2011年129-9]
- A significant subset of gliomas arises after activation of the proproliferative platelet-derived growth factor (PDGF) pathway. The progression of low-grade gliomas to more malignant tumors may be due to oncogenic cellula...
- Inhibition of VEGF induces cellular senescence in colorectal cancer cells
[作者:Hasan, MR; Ho, SHY; Owen, DA; Tai, IT,期刊:International Journal of Cancer, 页码:2115-2123 , 文章类型: Article,,卷期:2011年129-9]
- Vascular endothelial growth factor (VEGF) inhibitors, such as bevacizumab, have improved outcomes in metastatic colorectal cancer (CRC). Recent studies have suggested that VEGF can delay the onset of cellular senescence ...
- Human ZNF312b oncogene is regulated by Sp1 binding to its promoter region through DNA demethylation and histone acetylation in gastric cancer
[作者:Song, IS; Ha, GH; Kim, JM; Jeong, SY; Lee, HC; Kim, YS; Kim, YJ; Kwon, TK; Kim, NS,期刊:International Journal of Cancer, 页码:2124-2133 , 文章类型: Article,,卷期:2011年129-9]
- In a previous study, human ZNF312b was identified as a cell proliferation-associated oncogene via the K-ras/extracellular signal-regulated kinase cascade in gastric cancer. However, the mechanism concerning its transcrip...
- Polo-like kinase 1 regulates cell proliferation and is targeted by miR-593*in esophageal cancer
[作者:Ito, T; Sato, F; Kan, T; Cheng, YL; David, S; Agarwal, R; Paun, BC; Jin, Z; Olaru, AV; Hamilton, JP; Selaru, FM; Yang, J; Matsumura, N; Shimizu, K; Abraham, JM; Shimada, Y; Mori, Y; Meltzer, SJ,期刊:International Journal of Cancer, 页码:2134-2146 , 文章类型: Article,,卷期:2011年129-9]
- Polo-like kinase 1 (PLK1) is overexpressed in various human cancers. However, the biological functions and the post-transcriptional regulations of PLK1 in esophageal cancer (EC) are still unknown. The purposes of our stu...
- Long-term persistence of systemic and mucosal immune response to HPV-16/18 AS04-adjuvanted vaccine in preteen/adolescent girls and young women
[作者:Petaja, T; Pedersen, C; Poder, A; Strauss, G; Catteau, G; Thomas, F; Lehtinen, M; Descamps, D,期刊:International Journal of Cancer, 页码:2147-2157 , 文章类型: Article,,卷期:2011年129-9]
- Vaccination against oncogenic human papillomavirus (HPV) types is one key intervention for cervical cancer prevention. This follow-up study assessed the persistence of the systemic and mucosal immune responses together w...
- Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination
[作者:Bose, A; Taylor, JL; Alber, S; Watkins, SC; Garcia, JA; Rini, BI; Ko, JS; Cohen, PA; Finke, JH; Storkus, WJ,期刊:International Journal of Cancer, 页码:2158-2170 , 文章类型: Article,,卷期:2011年129-9]
- The multikinase inhibitor sunitinib malate (SUT) has been reported to reduce levels of myeloid suppressor cells and Treg cells in cancer patients, hypothetically diminishing intrinsic impediments for active immunization ...
- Lack of ex vivo peripheral and intrahepatic alpha-fetoprotein-specific CD4+responses in hepatocellular carcinoma
[作者:Witkowski, M; Spangenberg, HC; Neumann-Haefelin, C; Buttner, N; Breous, E; Kersting, N; Drognitz, O; Hopt, UT; Blum, HE; Semmo, N; Thimme, R,期刊:International Journal of Cancer, 页码:2171-2182 , 文章类型: Article,,卷期:2011年129-9]
- Hepatocellular carcinoma (HCC) is one of the most common malignancies with a poor prognosis and limited therapeutic options that is often characterized by the expression of the tumor-associated antigen a-fetoprotein (AFP...
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