- Therapeutics of Ebola Hemorrhagic Fever: Whole-Genome Transcriptional Analysis of Successful Disease Mitigation
[作者:Yen, JY; Garamszegi, S; Geisbert, JB; Rubins, KH; Geisbert, TW; Honko, A; Xia, Y; Connor, JH; Hensley, LE,期刊:Journal of Infectious Diseases, 页码:S1043-S1052 , 文章类型: Article,,卷期:2011年204-supl]
- The mechanisms of Ebola (EBOV) pathogenesis are only partially understood, but the dysregulation of normal host immune responses (including destruction of lymphocytes, increases in circulating cytokine levels, and develo...
- Kunjin Virus Replicon-Based Vaccines Expressing Ebola Virus Glycoprotein GP Protect the Guinea Pig Against Lethal Ebola Virus Infection
[作者:Reynard, O; Mokhonov, V; Mokhonova, E; Leung, J; Page, A; Mateo, M; Pyankova, O; Georges-Courbot, MC; Raoul, H; Khromykh, AA; Volchkov, VE,期刊:Journal of Infectious Diseases, 页码:S1060-S1065 , 文章类型: Article,,卷期:2011年204-supl]
- Pre- or postexposure treatments against the filoviral hemorrhagic fevers are currently not available for human use. We evaluated, in a guinea pig model, the immunogenic potential of Kunjin virus (KUN)-derived replicons a...
- Vesicular Stomatitis Virus-Based Ebola Vaccines With Improved Cross-Protective Efficacy
[作者:Marzi, A; Ebihara, H; Callison, J; Groseth, A; Williams, KJ; Geisbert, TW; Feldmann, H,期刊:Journal of Infectious Diseases, 页码:S1066-S1074 , 文章类型: Article,,卷期:2011年204-supl]
- For Ebola virus (EBOV), 4 different species are known: Zaire, Sudan, Cote d'Ivoire, and Reston ebolavirus. The newly discovered Bundibugyo ebolavirus has been proposed as a 5th species. So far, no cross-neutralization am...
- Single Immunization With a Monovalent Vesicular Stomatitis Virus-Based Vaccine Protects Nonhuman Primates Against Heterologous Challenge With Bundibugyo ebolavirus
[作者:Falzarano, D; Feldmann, F; Grolla, A; Leung, A; Ebihara, H; Strong, JE; Marzi, A; Takada, A; Jones, S; Gren, J; Geisbert, J; Jones, SM; Geisbert, TW; Feldmann, H,期刊:Journal of Infectious Diseases, 页码:S1082-S1089 , 文章类型: Article,,卷期:2011年204-supl]
- The recombinant vesicular stomatitis virus (rVSV) vector-based monovalent vaccine platform expressing a filovirus glycoprotein has been demonstrated to provide protection from lethal challenge with Ebola (EBOV) and Marbu...
- Protective Efficacy of a Bivalent Recombinant Vesicular Stomatitis Virus Vaccine in the Syrian Hamster Model of Lethal Ebola Virus Infection
[作者:Tsuda, Y; Safronetz, D; Brown, K; LaCasse, R; Marzi, A; Ebihara, H; Feldmann, H,期刊:Journal of Infectious Diseases, 页码:S1090-S1097 , 文章类型: Article,,卷期:2011年204-supl]
- Background. Outbreaks of filoviral hemorrhagic fever occur sporadically and unpredictably across wide regions in central Africa and overlap with the occurrence of other infectious diseases of public health importance. Me...
- Filovirus Outbreak Detection and Surveillance: Lessons From Bundibugyo
[作者:MacNeil, A; Farnon, EC; Morgan, OW; Gould, P; Boehmer, TK; Blaney, DD; Wiersma, P; Tappero, JW; Nichol, ST; Ksiazek, TG; Rollin, PE,期刊:Journal of Infectious Diseases, 页码:S761-S767 , 文章类型: Article,,卷期:2011年204-supl]
- The first outbreak of Ebola hemorrhagic fever (EHF) due to Bundibugyo ebolavirus occurred in Uganda from August to December 2007. During outbreak response and assessment, we identified 131 EHF cases (44 suspect, 31 proba...
- Risk Factors for Zaire ebolavirus-Specific IgG in Rural Gabonese Populations
[作者:Nkoghe, D; Padilla, C; Becquart, P; Wauquier, N; Moussavou, G; Akue, JP; Ollomo, B; Pourrut, X; Souris, M; Kazanji, M; Gonzalez, JP; Leroy, E,期刊:Journal of Infectious Diseases, 页码:S768-S775 , 文章类型: Article,,卷期:2011年204-supl]
- Methods. Blood samples and clinical and sociodemographic data were collected from 4349 adults and 362 children in a random sample of 220 villages in the 9 provinces of Gabon. An enzyme-linked immunosorbent assay was used...
- Emergence of Divergent Zaire Ebola Virus Strains in Democratic Republic of the Congo in 2007 and 2008
[作者:Grard, G; Biek, R; Tamfum, JJM; Fair, J; Wolfe, N; Formenty, P; Paweska, J; Leroy, E,期刊:Journal of Infectious Diseases, 页码:S776-S784 , 文章类型: Article,,卷期:2011年204-supl]
- Methods. Viruses of each outbreak were isolated and the full-length genomes were characterized. Phylogenetic analysis was then undertaken to characterize the relationships with previously described viruses. Results. The ...
- Management of Accidental Exposure to Ebola Virus in the Biosafety Level 4 Laboratory, Hamburg, Germany
[作者:Gunther, S; Feldmann, H; Geisbert, TW; Hensley, LE; Rollin, PE; Nichol, ST; Stroher, U; Artsob, H; Peters, CJ; Ksiazek, TG; Becker, S; ter Meulen, J; Olschlager, S; Schmidt-Chanasit, J; Sudeck, H; Burchard, GD; Schmiedel, S,期刊:Journal of Infectious Diseases, 页码:S785-S790 , 文章类型: Article,,卷期:2011年204-supl]
- A needlestick injury occurred during an animal experiment in the biosafety level 4 laboratory in Hamburg, Germany, in March 2009. The syringe contained Zaire ebolavirus (ZEBOV) mixed with Freund's adjuvant. Neither an ap...
- Filovirus Hemorrhagic Fever Outbreak Case Management: A Review of Current and Future Treatment Options
[作者:Roddy, P; Colebunders, R; Jeffs, B; Palma, PP; Van Herp, M; Borchert, M,期刊:Journal of Infectious Diseases, 页码:S791-S795 , 文章类型: Review,,卷期:2011年204-supl]
- We describe and discuss treatment possibilities, challenges, and potential next steps for FHF outbreak case management. More comprehensive supportive treatment, including vital sign monitoring, intensive care components,...
- Outbreak of Marburg Hemorrhagic Fever Among Miners in Kamwenge and Ibanda Districts, Uganda, 2007
[作者:Adjemian, J; Farnon, EC; Tschioko, F; Wamala, JF; Byaruhanga, E; Bwire, GS; Kansiime, E; Kagirita, A; Ahimbisibwe, S; Katunguka, F; Jeffs, B; Lutwama, JJ; Downing, R; Tappero, JW; Formenty, P; Amman, B; Manning, C; Towner, J; Nichol, ST; Rollin, PE,期刊:Journal of Infectious Diseases, 页码:S796-S799 , 文章类型: Article,,卷期:2011年204-supl]
- Marburg hemorrhagic fever was detected among 4 miners in Ibanda District, Uganda, from June through September, 2007. Infection was likely acquired through exposure to bats or bat secretions in a mine in Kamwenge District...
- Is Marburg Virus Enzootic in Gabon?
[作者:Maganga, GD; Bourgarel, M; Ella, GE; Drexler, JF; Gonzalez, JP; Drosten, C; Leroy, EM,期刊:Journal of Infectious Diseases, 页码:S800-S803 , 文章类型: Article,,卷期:2011年204-supl]
- Marburg virus (MARV) nucleic acid was detected in Rousettus aegyptiacus bats in 2005 and 2006 in the midwest and southeast of Gabon. In this study we used MARV-specific real-time reverse-transcription polyermase chain re...
- Ebola Reston Virus Infection of Pigs: Clinical Significance and Transmission Potential
[作者:Marsh, GA; Haining, J; Robinson, R; Foord, A; Yamada, M; Barr, JA; Payne, J; White, J; Yu, M; Bingham, J; Rollin, PE; Nichol, ST; Wang, LF; Middleton, D,期刊:Journal of Infectious Diseases, 页码:S804-S809 , 文章类型: Article,,卷期:2011年204-supl]
- In 2008, Reston ebolavirus (REBOV) was isolated from pigs during a disease investigation in the Philippines. Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine circovirus type 2 (PCV-2) infections we...
|