- Intensification of Antiretroviral Therapy With Raltegravir or Addition of Hyperimmune Bovine Colostrum in HIV-Infected Patients With Suboptimal CD4(+) T-Cell Response: A Randomized Controlled Trial
[作者:Byakwaga, H; Kelly, M; Purcell, DFJ; French, MA; Amin, J; Lewin, SR; Haskelberg, H; Kelleher, AD; Garsia, R; Boyd, MA; Cooper, DA; Emery, S,期刊:Journal of Infectious Diseases, 页码:1532-1540 , 文章类型: Article,,卷期:2011年204-10]
- Background. Despite virally suppressive combination antiretroviral therapy (cART), some HIV-infected patients exhibit suboptimal CD4(+) T-cell recovery. This study aimed to determine the effect of intensification of cART...
- Timing of Plasmid Cytokine (IL-2/Ig) Administration Affects HIV-1 Vaccine Immunogenicity in HIV-Seronegative Subjects
[作者:Baden, LR; Blattner, WA; Morgan, C; Huang, YD; Defawe, OD; Sobieszczyk, ME; Kochar, N; Tomaras, GD; McElrath, MJ; Russell, N; Brandariz, K; Cardinali, M; Graham, BS; Barouch, DH; Dolin, R,期刊:Journal of Infectious Diseases, 页码:1541-1549 , 文章类型: Article,,卷期:2011年204-10]
- Background. To investigate the potential immunostimulatory effect of interleukin (IL) 2 as a human immunodeficiency virus type 1 (HIV-1) vaccine adjuvant, we conducted a study of a plasmid coding for a fusion protein of ...
- Immune Activation in the Female Genital Tract During HIV Infection Predicts Mucosal CD4 Depletion and HIV Shedding
[作者:Jaspan, HB; Liebenberg, L; Hanekom, W; Burgers, W; Coetzee, D; Williamson, AL; Little, F; Myer, L; Coombs, RW; Sodora, D; Passmore, JA,期刊:Journal of Infectious Diseases, 页码:1550-1556 , 文章类型: Article,,卷期:2011年204-10]
- Plasma viral load predicts genital tract human immunodeficiency virus (HIV) shedding in HIV-infected women. We investigated whether local mucosal T-cell activation (HLA-DR, CD38, CCR5, and Ki67) contributed to HIV sheddi...
- Dendritic Cell Dysfunction During Primary HIV-1 Infection
[作者:Huang, JH; Yang, Y; Al-Mozaini, M; Burke, PS; Beamon, J; Carrington, MF; Seiss, K; Rychert, J; Rosenberg, ES; Lichterfeld, M; Yu, XG,期刊:Journal of Infectious Diseases, 页码:1557-1562 , 文章类型: Article,,卷期:2011年204-10]
- Dendritic cells have critical roles for generating and fine-tuning adaptive immune responses and for regulating immune activity through cytokine secretion. In this study, we analyzed functional properties of dendritic ce...
- Recombinant BCG Delta ureC hly plus Induces Superior Protection Over Parental BCG by Stimulating a Balanced Combination of Type 1 and Type 17 Cytokine Responses
[作者:Desel, C; Dorhoi, A; Bandermann, S; Grode, L; Eisele, B; Kaufmann, SHE,期刊:Journal of Infectious Diseases, 页码:1573-1584 , 文章类型: Article,,卷期:2011年204-10]
- Background. New vaccines against tuberculosis (TB) are urgently needed because the only available vaccine, Mycobacterium bovis bacillus Calmette-Guerin (BCG), fails to protect against pulmonary TB in adults. The recombin...
- Streptococcus pneumoniae Serotype 9A Isolates Contain Diverse Mutations to wcjE That Result in Variable Expression of Serotype 9V-specific Epitope
[作者:Calix, JJ; Oliver, MB; Sherwood, LK; Beall, B; Hollingshead, SK; Nahm, MH,期刊:Journal of Infectious Diseases, 页码:1585-1595 , 文章类型: Article,,卷期:2011年204-10]
- Background. Streptococcus pneumoniae is a significant pathogen capable of expressing protective and antigenically diverse capsules. To better understand the molecular basis of capsular antigenic diversity, we investigate...
- Synthesis and Distribution of CARDS Toxin During Mycoplasma pneumoniae Infection in a Murine Model
[作者:Kannan, TR; Coalson, JJ; Cagle, M; Musatovova, O; Hardy, RD; Baseman, JB,期刊:Journal of Infectious Diseases, 页码:1596-1604 , 文章类型: Article,,卷期:2011年204-10]
- Mice were infected with Mycoplasma pneumoniae and monitored for the synthesis and distribution of the unique adenosine diphosphate-ribosylating and vacuolating Community Acquired Respiratory Distress Syndrome (CARDS) tox...
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