Novel beta-amino esters bearing a bioactive benzothiazole moiety were obtained with high enantioselectivities (up to 95% ee) through a Mannich-type reaction of different imines with malonate in the presence of a new chir...
A bisimidazoline compound has been prepared as a new chiral solvating agent starting from isophthalaldehyde and (S, S)-1,2-diphenylethylenediamine through a single-step synthesis. In the presence of one equivalent of thi...
A phosphane-free copper-catalyzed decarboxylative cross-coupling reaction of alkynyl carboxylic acids with aryl halides was developed. CuBr (1-5 mol-%) was used as a catalyst in the presence of a beta-diketone ligand in ...
Domino C-Se cross-coupling of 2-(iodoaryl)selenoureas with aryl iodides has been accomplished in the presence of a copper(I)-1,1-phenanthroline complex at moderate temperature. The reactions involve intra-and intermolecu...
In the present study, the iron-catalyzed dehydration of a range of amides to the corresponding nitriles by using N-methyl-N-(trimethylsilyl) trifluoroacetamide (MSTFA) as the dehydration reagent has been explored. After ...
Pyrano-naphthoquinones fused to gamma-lactone ring are structurally and biologically interesting natural products. We have accomplished an enantioselective synthesis of (-)-arizonin C1 (2d) in nine steps. We employed the...
A library of new fluorescent molecular rotors (FMRs) for viscosity sensing was synthesized. The sensitivity of the fluorescence emission toward solvent viscosity and polarity was investigated by using UV/Vis absorption, ...
Highly efficient blue fluorescent materials with a 2-diphenylaminofluoren-7-ylstyrene emitting unit and various aromatic end-capping groups were synthesized and characterized. A 2-methyl-9,10-bis(2-naphthyl)anthracene ho...
Coumarin-based receptor R1 recognizes Ni(2+) at sub-micromolar levels in aqueous ethanolic medium (60: 40) at physiological pH and exhibited INH logic function at pH values below 7. Additionally, this system showed recon...
1,3-Dipolar cycloadditions of C-carboxymethyl-N-arylnitrile imines with cyclic alpha,beta-unsaturated ketones of various sizes have been studied. After cycloaddition, oxidative aromatization gives the ring-fused pyrazole...
2,5-Disubstituted furans were synthesized by one-flask Heck arylation/oxidation sequences. The starting materials are 2-substituted 2,3-dihydrofurans, conveniently available by RCM/isomerization sequences, and arenediazo...