- Simultaneous in vivo tracking of dendritic cells and priming of an antigen-specific immune response
[作者:Noh, YW; Jang, YS; Ahn, KJ; Lim, YT; Chung, BH,期刊:BIOMATERIALS, 页码:6254-6263 , 文章类型: Article,,卷期:2011年32-26]
- We report the fabrication of a one-pot antigen system that delivers antigen to dendritic cells (DCs) and tracks their in vivo migration after injection. Multifunctional polymer nanoparticles containing ovalbumin protein,...
- A gene delivery system for human cells mediated by both a cell-penetrating peptide and a piggyBac transposase
[作者:Lee, CY; Li, JF; Liou, JS; Charng, YC; Huang, YW; Lee, HJ,期刊:BIOMATERIALS, 页码:6264-6276 , 文章类型: Article,,卷期:2011年32-26]
- The piggyBac (PB) transposable element has recently accumulated enormous attention as a tool for the transgenesis in various eukaryotic organisms. Arginine-rich cell-penetrating peptides (CPPs) are protein transduction d...
- Controlled release of DNA from poly(vinylpyrrolidone) capsules using cleavable linkers
[作者:Ng, SL; Such, GK; Johnston, APR; Antequera-Garcia, G; Caruso, F,期刊:BIOMATERIALS, 页码:6277-6284 , 文章类型: Article,,卷期:2011年32-26]
- The design of polymer carriers with tunable degradation and cargo release is fundamental for applications in drug and gene delivery. In this study, we report low-fouling poly(N-vinyl pyrrolidone) (PVPON) capsules assembl...
- Drug carrier nanoparticles that penetrate human chronic rhinosinusitis mucus
[作者:Lai, SK; Suk, JS; Pace, A; Wang, YY; Yang, M; Mert, O; Chen, J; Kim, J; Hanes, J,期刊:BIOMATERIALS, 页码:6285-6290 , 文章类型: Article,,卷期:2011年32-26]
- No effective therapies currently exist for chronic rhinosinusitis (CRS), a persistent inflammatory condition characterized by the accumulation of highly viscoelastic mucus (CRSM) in the sinuses. Nanoparticle therapeutics...
- Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles
[作者:Cole, AJ; David, AE; Wang, JX; Galban, CJ; Yang, VC,期刊:BIOMATERIALS, 页码:6291-6301 , 文章类型: Article,,卷期:2011年32-26]
- Magnetic iron oxide nanoparticles (MNPs) have been studied to circumvent the limitations of status-quo brain tumor therapy and can be targeted by applying an external magnetic field to lesions. To address the pharmacokin...
- Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery
[作者:Tagalakis, AD; He, L; Saraiva, L; Gustafsson, KT; Hart, SL,期刊:BIOMATERIALS, 页码:6302-6315 , 文章类型: Article,,卷期:2011年32-26]
- RNA interference induced by double-stranded, small interfering RNA (siRNA) molecules has attracted great attention as a genetic therapeutic approach. Despite major advances in this field, new nanoparticle formulations ar...
- Targeted delivery of non-viral vectors to cartilage in vivo using a chondrocyte-homing peptide identified by phage display
[作者:Pi, YB; Zhang, X; Shi, JJ; Zhu, JX; Chen, WQ; Zhang, CG; Gao, WW; Zhou, CY; Ao, YF,期刊:BIOMATERIALS, 页码:6324-6332 , 文章类型: Article,,卷期:2011年32-26]
- Gene therapy is a promising method for osteoarthritis and cartilage injury. However, specifically delivering target genes into chondrocytes is a great challenge because of their non-vascularity and the dense extracellula...
- KALA-modified multi-layered nanoparticles as gene carriers for MHC class-I mediated antigen presentation for a DNA vaccine
[作者:Shaheen, SM; Akita, H; Nakamura, T; Takayama, S; Futaki, S; Yamashita, A; Katoono, R; Yui, N; Harashima, H,期刊:BIOMATERIALS, 页码:6342-6350 , 文章类型: Article,,卷期:2011年32-26]
- DNA vaccines are a new-generation vaccines that elicit an immunological response against a wide-variety of antigens with frequent mutations. However, an effective non-viral vector for genetically engineered DNA to dendri...
- Robust CNS regeneration after complete spinal cord transection using aligned poly-L-lactic acid microfibers
[作者:Hurtado, A; Cregg, JM; Wang, HB; Wendell, DF; Oudega, M; Gilbert, RJ; McDonald, JW,期刊:BIOMATERIALS, 页码:6068-6079 , 文章类型: Article,,卷期:2011年32-26]
- Following spinal cord injury, axons fail to regenerate without exogenous intervention. In this study we report that aligned microfiber-based grafts foster robust regeneration of vascularized CNS tissue. Film, random, and...
- The enhancement of mature vessel formation and cardiac function in infarcted hearts using dual growth factor delivery with self-assembling peptides
[作者:Kim, JH; Jung, Y; Kim, SH; Sun, K; Choi, J; Kim, HC; Park, Y; Kim, SH,期刊:BIOMATERIALS, 页码:6080-6088 , 文章类型: Article,,卷期:2011年32-26]
- For successful treatment of myocardial infarction (MI), it is important to prevent cardiac fibrosis and maintain cardiac function by protecting cardiomyocytes and inducing angiogenesis. To establish functional and stable...
- Pro-osteogenic trophic effects by PKA activation in human mesenchymal stromal cells
[作者:Doorn, J; van de Peppel, J; van Leeuwen, JPTM; Groen, N; van Blitterswijk, CA; de Boer, J,期刊:BIOMATERIALS, 页码:6089-6098 , 文章类型: Article,,卷期:2011年32-26]
- Human mesenchymal stromal cells (hMSCs) are able to differentiate into a wide variety of cell types, which makes them an interesting source for tissue engineering applications. On the other hand, these cells also secrete...
|