- TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis
[作者:Petersson, M; Brylka, H; Kraus, A; John, S; Rappl, G; Schettina, P; Niemann, C,期刊:EMBO journal, 页码:3004-3018 , 文章类型: Article,,卷期:2011年30-15]
- Mammalian epidermis consists of the interfollicular epidermis, hair follicles (HFs) and associated sebaceous glands (SGs). It is constantly renewed by stem and progenitor cell populations that have been identified and ea...
- Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1
[作者:Robinson, JLL; MacArthur, S; Ross-Innes, CS; Tilley, WD; Neal, DE; Mills, IG; Carroll, JS,期刊:EMBO journal, 页码:3019-3027 , 文章类型: Article,,卷期:2011年30-15]
- Breast cancer is a heterogeneous disease and several distinct subtypes exist based on differential gene expression patterns. Molecular apocrine tumours were recently identified as an additional subgroup, characterised as...
- DNA methylation status predicts cell type-specific enhancer activity
[作者:Wiench, M; John, S; Baek, S; Johnson, TA; Sung, MH; Escobar, T; Simmons, CA; Pearce, KH; Biddie, SC; Sabo, PJ; Thurman, RE; Stamatoyannopoulos, JA; Hager, GL,期刊:EMBO journal, 页码:3028-3039 , 文章类型: Article,,卷期:2011年30-15]
- Cell-selective glucocorticoid receptor (GR) binding to distal regulatory elements is associated with cell type-specific regions of locally accessible chromatin. These regions can either pre-exist in chromatin (pre-progra...
- Linking the branchpoint helix to a newly found receptor allows lariat formation by a group II intron
[作者:Li, CF; Costa, M; Michel, F,期刊:EMBO journal, 页码:3040-3051 , 文章类型: Article,,卷期:2011年30-15]
- Like spliceosomal introns, the ribozyme-containing group II introns are excised as branched, lariat structures: a 2'-5' bond is created between the first nucleotide of the intron and an adenosine in domain VI, a componen...
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