- Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission
[作者:Zhao, J; Liu, T; Jin, SB; Wang, XM; Qu, MQ; Uhlen, P; Tomilin, N; Shupliakov, O; Lendahl, U; Nister, M,期刊:EMBO journal, 页码:2762-2778 , 文章类型: Article,,卷期:2011年30-14]
- Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Drp1 (dynamin-related protein 1) and hFis1 are two key players of mitochondrial fission, but how Drp1 is recruited to mitochondria and...
- A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis
[作者:Buttner, S; Ruli, D; Vogtle, FN; Galluzzi, L; Moitzi, B; Eisenberg, T; Kepp, O; Habernig, L; Carmona-Gutierrez, D; Rockenfeller, P; Laun, P; Breitenbach, M; Khoury, C; Frohlich, KU; Rechberger, G; Meisinger, C; Kroemer, G; Madeo, F,期刊:EMBO journal, 页码:2779-2792 , 文章类型: Article,,卷期:2011年30-14]
- Mitochondrial outer membrane permeabilization is a watershed event in the process of apoptosis, which is tightly regulated by a series of pro- and anti-apoptotic proteins belonging to the BCL-2 family, each characteristi...
- A synthetic prestin reveals protein domains and molecular operation of outer hair cell piezoelectricity
[作者:Schaechinger, TJ; Gorbunov, D; Halaszovich, CR; Moser, T; Kugler, S; Fakler, B; Oliver, D,期刊:EMBO journal, 页码:2793-2804 , 文章类型: Article,,卷期:2011年30-14]
- Prestin, a transporter-like protein of the SLC26A family, acts as a piezoelectric transducer that mediates the fast electromotility of outer hair cells required for cochlear amplification and auditory acuity in mammals. ...
- The Sm-like RNA chaperone Hfq mediates transcription antitermination at Rho-dependent terminators
[作者:Rabhi, M; Espeli, O; Schwartz, A; Cayrol, B; Rahmouni, AR; Arluison, V; Boudvillain, M,期刊:EMBO journal, 页码:2805-2816 , 文章类型: Article,,卷期:2011年30-14]
- In Escherichia coli, the essential motor protein Rho promotes transcription termination in a tightly controlled manner that is not fully understood. Here, we show that the general post-transcriptional regulatory protein ...
- Drosophila Set1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription
[作者:Ardehali, MB; Mei, A; Zobeck, KL; Caron, M; Lis, JT; Kusch, T,期刊:EMBO journal, 页码:2817-2828 , 文章类型: Article,,卷期:2011年30-14]
- Histone H3 lysine 4 trimethylation (H3K4me3) is a major hallmark of promoter-proximal histones at transcribed genes. Here, we report that a previously uncharacterized Drosophila H3K4 methyltransferase, dSet1, and not the...
- Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
[作者:Bian, CB; Xu, C; Ruan, JB; Lee, KK; Burke, TL; Tempel, W; Barsyte, D; Li, J; Wu, MH; Zhou, BO; Fleharty, BE; Paulson, A; Allali-Hassani, A; Zhou, JQ; Mer, G; Grant, PA; Workman, JL; Zang, JY; Min, JR,期刊:EMBO journal, 页码:2829-2842 , 文章类型: Article,,卷期:2011年30-14]
- The SAGA (Spt-Ada-Gcn5 acetyltransferase) complex is an important chromatin modifying complex that can both acetylate and deubiquitinate histones. Sgf29 is a novel component of the SAGA complex. Here, we report the cryst...
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