The convenient synthesis of a library of pyrimidine-isoxazoline hybrids in 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim][PF(6)])-water/potassium hydroxide at ambient temperature has been accomplished. The ionic...
An efficient synthesis of various N-substituted 3-aminoindazoles using Buchwald-Hartwig C-N coupling reaction is described. Several parameters were varied, including the nature of the halogen atom and the protecting grou...
Stereoselective routes to cis-(2S,3R)-3-hydroxypipecolic acid and two enantiomeric cis-2-hydroxymethyl-3-hydroxypiperidine derivatives from a common precursor have been developed, which featured stereocontrolled vinylati...
A library of 5-aryl-3(2H)-furanones that are modified in the alpha-position of the alpha,beta-unsaturated carbonyl system was prepared via simple one-to three-step transformations from one common scaffold. The (13)C NMR ...