- The zinc-finger protein SEA-2 regulates larval developmental timing and adult lifespan in C. elegans
[作者:Huang, XX; Zhang, H; Zhang, H,期刊:Development, 页码:2059-2068 , 文章类型: Article,,卷期:2011年138-10]
- Like other biological processes, aging is regulated by genetic pathways. However, it remains largely unknown whether aging is determined by an innate programmed timing mechanism and, if so, how this timer is linked to th...
- Polar-localized NPH3-like proteins regulate polarity and endocytosis of PIN-FORMED auxin efflux carriers
[作者:Furutani, M; Sakamoto, N; Yoshida, S; Kajiwara, T; Robert, HS; Friml, J; Tasaka, M,期刊:Development, 页码:2069-2078 , 文章类型: Article,,卷期:2011年138-10]
- PIN-FORMED (PIN)-dependent auxin transport is essential for plant development and its modulation in response to the environment or endogenous signals. A NON-PHOTOTROPIC HYPOCOTYL 3 (NPH3)-like protein, MACCHI-BOU 4 (MAB4...
- Primary cilia control telencephalic patterning and morphogenesis via Gli3 proteolytic processing
[作者:Besse, L; Neti, M; Anselme, I; Gerhardt, C; Ruther, U; Laclef, C; Schneider-Maunoury, S,期刊:Development, 页码:2079-2088 , 文章类型: Article,,卷期:2011年138-10]
- Primary cilia have essential functions in vertebrate development and signaling. However, little is known about cilia function in brain morphogenesis, a process that is severely affected in human ciliopathies. Here, we st...
- Nephric duct insertion is a crucial step in urinary tract maturation that is regulated by a Gata3-Raldh2-Ret molecular network in mice
[作者:Chia, I; Grote, D; Marcotte, M; Batourina, E; Mendelsohn, C; Bouchard, M,期刊:Development, 页码:2089-2097 , 文章类型: Article,,卷期:2011年138-10]
- Urinary tract development depends on a complex series of events in which the ureter moves from its initial branch point on the nephric duct (ND) to its final insertion site in the cloaca (the primitive bladder and urethr...
- p120 catenin is required for normal renal tubulogenesis and glomerulogenesis
[作者:Marciano, DK; Brakeman, PR; Lee, CZ; Spivak, N; Eastburn, DJ; Bryant, DM; Beaudoin, GM; Hofmann, I; Mostov, KE; Reichardt, LF,期刊:Development, 页码:2099-2109 , 文章类型: Article,,卷期:2011年138-10]
- Defects in the development or maintenance of tubule diameter correlate with polycystic kidney disease. Here, we report that absence of the cadherin regulator p120 catenin (p120ctn) from the renal mesenchyme prior to tubu...
- Flt1 acts as a negative regulator of tip cell formation and branching morphogenesis in the zebrafish embryo
[作者:Krueger, J; Liu, D; Scholz, K; Zimmer, A; Shi, Y; Klein, C; Siekmann, A; Schulte-Merker, S; Cudmore, M; Ahmed, A; le Noble, F,期刊:Development, 页码:2111-2120 , 文章类型: Article,,卷期:2011年138-10]
- Endothelial tip cells guide angiogenic sprouts by exploring the local environment for guidance cues such as vascular endothelial growth factor (VegfA). Here we present Flt1 (Vegf receptor 1) loss-and gain-of-function dat...
- The nucleoporin Seh1 forms a complex with Mio and serves an essential tissue-specific function in Drosophila oogenesis
[作者:Senger, S; Csokmay, J; Tanveer, A; Jones, TI; Sengupta, P; Lilly, MA,期刊:Development, 页码:2133-2142 , 文章类型: Article,,卷期:2011年138-10]
- The nuclear pore complex (NPC) mediates the transport of macromolecules between the nucleus and cytoplasm. Recent evidence indicates that structural nucleoporins, the building blocks of the NPC, have a variety of unantic...
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