- Evidence for Differences in Immunologic and Pathogenesis Properties of Herpes Simplex Virus 2 Strains From the United States and South Africa
[作者:Dudek, TE; Torres-Lopez, E; Crumpacker, C; Knipe, DM,期刊:Journal of Infectious Diseases, 页码:1434-1441 , 文章类型: Article,,卷期:2011年203-10]
- Methods. To test whether a current vaccine candidate can protect against HSV-2 from Sub-Saharan Africa, we examined the ability of an HSV-2 vaccine strain, dl5-29, and other HSV-2 replication-defective mutant strains to ...
- Norovirus GII-4 Causes a More Severe Gastroenteritis Than Other Noroviruses in Young Children
[作者:Huhti, L; Szakal, ED; Puustinen, L; Salminen, M; Huhtala, H; Valve, O; Blazevic, V; Vesikari, T,期刊:Journal of Infectious Diseases, 页码:1442-1444 , 文章类型: Article,,卷期:2011年203-10]
- Norovirus (NoV) GII-4 has emerged as the predominant NoV genotype in outbreaks of gastroenteritis worldwide. We determined clinical features of NoV GII-4 associated acute gastroenteritis (AGE) in comparison with AGE asso...
- A High-Throughput Screen Targeting Malaria Transmission Stages Opens New Avenues for Drug Development
[作者:Buchholz, K; Burke, TA; Williamson, KC; Wiegand, RC; Wirth, DF; Marti, M,期刊:Journal of Infectious Diseases, 页码:1445-1453 , 文章类型: Article,,卷期:2011年203-10]
- A major goal of the worldwide malaria eradication program is the reduction and eventual elimination of malaria transmission. All currently available antimalarial compounds were discovered on the basis of their activity a...
- Nitric Oxide Protection Against Murine Cerebral Malaria Is Associated With Improved Cerebral Microcirculatory Physiology
[作者:Cabrales, P; Zanini, GM; Meays, D; Frangos, JA; Carvalho, LJM,期刊:Journal of Infectious Diseases, 页码:1454-1463 , 文章类型: Article,,卷期:2011年203-10]
- Cerebral malaria (CM) is a leading cause of death in Plasmodium falciparum infections. In the Plasmodium berghei ANKA (PbA) murine model, CM pathogenesis is associated with low nitric oxide (NO) bioavailability and brain...
- Differential Changes in Expression of Intestinal Antimicrobial Peptide Genes During Ascaris lumbricoides Infection in Zambian Adults Do Not Respond to Helminth Eradication
[作者:Kapulu, MC; Simuyandi, M; Sianongo, S; Mutale, M; Katubulushi, M; Kelly, P,期刊:Journal of Infectious Diseases, 页码:1464-1473 , 文章类型: Article,,卷期:2011年203-10]
- Methods. Case patients (n = 27) and control subjects (n = 44) underwent enteroscopy for collection of jejunal biopsy specimens, which were used in quantitative, real-time reverse-transcription polymerase chain reaction f...
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