- Nef Inhibits Glucose Uptake in Adipocytes and Contributes to Insulin Resistance in Human Immunodeficiency Virus Type I Infection
[作者:Cheney, L; Hou, JC; Morrison, S; Pessin, J; Steigbigel, RT,期刊:Journal of Infectious Diseases, 页码:1824-1831 , 文章类型: Article,,卷期:2011年203-12]
- Human immunodeficiency virus (HIV) infection is associated with insulin resistance. HIV type 1 Nef downregulates cell surface protein expression, alters signal transduction, and interacts with the cytoskeleton and protei...
- Dose-Finding Study of the Novel Tuberculosis Vaccine, MVA85A, in Healthy BCG-Vaccinated Infants
[作者:Scriba, TJ; Tameris, M; Mansoor, N; Smit, E; van der Merwe, L; Mauff, K; Hughes, EJ; Moyo, S; Brittain, N; Lawrie, A; Mulenga, H; de Kock, M; Gelderbloem, S; Veldsman, A; Hatherill, M; Geldenhuys, H; Hill, AVS; Hussey, GD; Mahomed, H; Hanekom, WA; McShane, H,期刊:Journal of Infectious Diseases, 页码:1832-1843 , 文章类型: Article,,卷期:2011年203-12]
- Background. BCG, the only licensed tuberculosis vaccine, affords poor protection against lung tuberculosis in infants and children. A new tuberculosis vaccine, which may enhance the BCG-induced immune response, is urgent...
- Escherichia coli Isolates Causing Bacteremia via Gut Translocation and Urinary Tract Infection in Young Infants Exhibit Different Virulence Genotypes
[作者:Mahjoub-Messai, F; Bidet, P; Caro, V; Diancourt, L; Biran, V; Aujard, Y; Bingen, E; Bonacorsi, S,期刊:Journal of Infectious Diseases, 页码:1844-1849 , 文章类型: Article,,卷期:2011年203-12]
- Escherichia coli bacteremia in young infants may arise via either urinary tract infection or gut translocation (GT). E. coli GT isolates have rarely been investigated. Molecular analysis of 100 E. coli isolates recovered...
- Osteopontin Impairs Host Defense During Pneumococcal Pneumonia
[作者:van der Windt, GJW; Hoogendijk, AJ; Schouten, M; Hommes, TJ; de Vos, AF; Florquin, S; van der Poll, T,期刊:Journal of Infectious Diseases, 页码:1850-1858 , 文章类型: Article,,卷期:2011年203-12]
- Methods. To determine the role of osteopontin in the host response during pneumococcal pneumonia, osteopontin knockout (KO) and normal wild-type (WT) mice were intranasally infected with viable S. pneumoniae. Results. Pn...
- A Haemophilus ducreyi CpxR Deletion Mutant Is Virulent in Human Volunteers
[作者:Labandeira-Rey, M; Dodd, D; Fortney, KR; Zwickl, B; Katz, BP; Janowicz, DM; Spinola, SM; Hansen, EJ,期刊:Journal of Infectious Diseases, 页码:1859-1865 , 文章类型: Article,,卷期:2011年203-12]
- Haemophilus ducreyi 35000HP contains a homolog of the CpxRA 2-component signal transduction system, which controls the cell envelope stress response system in other gram-negative bacteria and regulates some important H. ...
- RTX Toxin Enhances the Survival of Vibrio vulnificus During Infection by Protecting the Organism From Phagocytosis
[作者:Lo, HR; Lin, JH; Chen, YH; Chen, CL; Shao, CP; Lai, YC; Hor, LI,期刊:Journal of Infectious Diseases, 页码:1866-1874 , 文章类型: Article,,卷期:2011年203-12]
- Vibrio vulnificus is a marine bacterium causing serious septicemia and wound infection in humans. It produces an RTX toxin that can lyse a variety of cells and is important for virulence in mice. In this study, we explor...
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