- Species-Specific Telomere Length Differences Between Blastocyst Cell Compartments and Ectopic Telomere Extension in Early Bovine Embryos by Human Telomerase Reverse Transcriptase
[作者:Iqbal, K; Kues, WA; Baulain, U; Garrels, W; Herrmann, D; Niemann, H,期刊:Biology of Reproduction, 页码:723-733 , 文章类型: Article,,卷期:2011年84-4]
- The enzyme telomerase is active in germ cells and is critically involved in maintenance of telomere length in successive generations. In preimplantation mammalian embryos, telomerase activity is present from the morula s...
- Endocrine Disrupter Bisphenol A Increases In Situ Estrogen Production in the Mouse Urogenital Sinus
[作者:Arase, S; Ishii, K; Igarashi, K; Aisaki, K; Yoshio, Y; Matsushima, A; Shimohigashi, Y; Arima, K; Kanno, J; Sugimura, Y,期刊:Biology of Reproduction, 页码:734-742 , 文章类型: Article,,卷期:2011年84-4]
- The balance between androgens and estrogens is very important in the development of the prostate, and even small changes in estrogen levels, including those of estrogen-mimicking chemicals, can lead to serious changes. B...
- Inhibition of PIK3 Signaling Pathway Members by the Ovotoxicant 4-Vinylcyclohexene Diepoxide in Rats
[作者:Keating, AF; Fernandez, SM; Mark-Kappeler, CJ; Sen, N; Sipes, IG; Hoyer, PB,期刊:Biology of Reproduction, 页码:743-751 , 文章类型: Article,,卷期:2011年84-4]
- 4-Vinylcyclohexene diepoxide (VCD), an occupational chemical that specifically destroys primordial and small primary follicles in the ovaries of rats and mice, is thought to target an oocyte-expressed tyrosine kinase rec...
- Association of the Q223R Polymorphism with Age at Menarche in the Leptin Receptor Gene in Humans
[作者:Riestra, P; Garcia-Anguita, A; Torres-Cantero, A; Bayonas, MJ; de Oya, M; Garces, C,期刊:Biology of Reproduction, 页码:752-755 , 文章类型: Article,,卷期:2011年84-4]
- Although genetics clearly influences the onset of menarche, the association of age at menarche (AAM) with variants in genes related to energy homeostasis remains unexplored. Our aim was to analyze the relationship of the...
- WDR82, a Key Epigenetics-Related Factor, Plays a Crucial Role in Normal Early Embryonic Development in Mice
[作者:Bi, Y; Lv, Z; Wang, Y; Hai, T; Huo, R; Zhou, ZM; Zhou, Q; Sha, JH,期刊:Biology of Reproduction, 页码:756-764 , 文章类型: Article,,卷期:2011年84-4]
- Epigenetic regulation is considered one of the most important mechanisms by which changes in gene expression occur without changes in the underlying DNA sequence. More and more studies have shown that this kind of regula...
- Breast Cancer-Resistance Protein (BCRP1) in the Fetal Mouse Brain: Development and Glucocorticoid Regulation
[作者:Petropoulos, S; Gibb, W; Matthews, SG,期刊:Biology of Reproduction, 页码:783-789 , 文章类型: Article,,卷期:2011年84-4]
- Breast cancer-resistance protein (BCRP1), encoded by Abcg2 mRNA, limits the penetration of a spectrum of compounds into the brain. The fetal brain is a primary target for many BCRP1 substrates; however, the developmental...
- Uncovering Gene Regulatory Networks During Mouse Fetal Germ Cell Development
[作者:Rolland, AD; Lehmann, KP; Johnson, KJ; Gaido, KW; Koopman, P,期刊:Biology of Reproduction, 页码:790-800 , 文章类型: Article,,卷期:2011年84-4]
- The commitment of germ cells to either oogenesis or spermatogenesis occurs during fetal gonad development: germ cells enter meiosis or mitotic arrest, depending on whether they reside within an ovary or a testis, respect...
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