- TLR4 Recognizes Pseudallescheria boydii Conidia and Purified Rhamnomannans
[作者:Figueiredo, RT; Fernandez, PL; Dutra, FF; Gonzalez, Y; Lopes, LC; Bittencourt, VCB; Sassaki, GL; Barreto-Bergter, E; Bozza, MT,期刊:Journal of Biological Chemistry, 页码:U161-U168 , 文章类型: Article,,卷期:2010年285-52]
- Pseudallescheria boydii (Scedosporium apiospermum) is a saprophytic fungus widespread in the environment, and has recently emerged as an agent of localized as well as disseminated infections, particularly mycetoma, in im...
- Leukotriene B-4 Augments and Restores Fc gamma Rs-dependent Phagocytosis in Macrophages
[作者:Okamoto, F; Saeki, K; Sumimoto, H; Yamasaki, S; Yokomizo, T,期刊:Journal of Biological Chemistry, 页码:U161-U168 , 文章类型: Article,,卷期:2010年285-52]
- Phagocytosis by macrophages is essential for host defense, i.e. preventing invasion of pathogens and foreign materials. Macrophages engulf immunoglobulin G (IgG)-opsonized particles through the action of the receptors fo...
- Inhibitory Phosphorylation of GSK-3 by CaMKII Couples Depolarization to Neuronal Survival
[作者:Song, B; Lai, BQ; Zheng, ZH; Zhang, YY; Luo, JY; Wang, C; Chen, YA; Woodgett, JR; Li, MT,期刊:Journal of Biological Chemistry, 页码:U161-U168 , 文章类型: Article,,卷期:2010年285-52]
- Glycogen synthase kinase-3 (GSK-3) plays a critical role in neuronal apoptosis. The two mammalian isoforms of the kinase, GSK-3 alpha and GSK-3 beta, are inhibited by phosphorylation at Ser-21 and Ser-9, respectively. De...
- Resting State Orai1 Diffuses as Homotetramer in the Plasma Membrane of Live Mammalian Cells
[作者:Madl, J; Weghuber, J; Fritsch, R; Derler, I; Fahrner, M; Frischauf, I; Lackner, B; Romanin, C; Schutz, GJ,期刊:Journal of Biological Chemistry, 页码:U161-U168 , 文章类型: Article,,卷期:2010年285-52]
- Store-operated calcium entry is essential for many signaling processes in nonexcitable cells. The best studied store-operated calcium current is the calcium release-activated calcium (CRAC) current in T-cells and mast ce...
- Phosphorylated alpha-Synuclein at Ser-129 Is Targeted to the Proteasome Pathway in a Ubiquitin-independent Manner
[作者:Machiya, Y; Hara, S; Arawaka, S; Fukushima, S; Sato, H; Sakamoto, M; Koyama, S; Kato, T,期刊:Journal of Biological Chemistry, 页码:U161-U168 , 文章类型: Article,,卷期:2010年285-52]
- alpha-Synuclein (a-Syn) is a major component of fibrillar aggregates in Lewy bodies (LBs), a characteristic hallmark of Parkinson disease. Almost 90% of a-Syn deposited in LBs is phosphorylated at Ser-129. However, the r...
- Functional Complementation and Genetic Deletion Studies of KirBac Channels ACTIVATORY MUTATIONS HIGHLIGHT GATING-SENSITIVE DOMAINS
[作者:Paynter, JJ; Andres-Enguix, I; Fowler, PW; Tottey, S; Cheng, W; Enkvetchakul, D; Bavro, VN; Kusakabe, Y; Sansom, MSP; Robinson, NJ; Nichols, CG; Tucker, SJ,期刊:Journal of Biological Chemistry, 页码:U161-U168 , 文章类型: Article,,卷期:2010年285-52]
- The superfamily of prokaryotic inwardly rectifying (KirBac) potassium channels is homologous to mammalian Kir channels. However, relatively little is known about their regulation or about their physiological role in vivo...
- The Heparan Sulfate Motif (GlcNS6S-IdoA2S)(3), Common in Heparin, Has a Strict Topography and Is Involved in Cell Behavior and Disease
[作者:Smits, NC; Kurup, S; Rops, AL; ten Dam, GB; Massuger, LF; Hafmans, T; Turnbull, JE; Spillmann, D; Li, JP; Kennel, SJ; Wall, JS; Shworak, NW; Dekhuijzen, PNR; van der Vlag, J; van Kuppevelt, TH,期刊:Journal of Biological Chemistry, 页码:U161-U168 , 文章类型: Article,,卷期:2010年285-52]
- Heparan sulfate (HS) is a structurally complex polysaccharide that interacts with a broad spectrum of extracellular effector ligands and thereby is thought to regulate a diverse array of biologic processes. The specifici...
- Phosphorylation of p50 NF-kappa B at a Single Serine Residue by DNA-dependent Protein Kinase Is Critical for VCAM-1 Expression upon TNF Treatment
[作者:Ju, JH; Naura, AS; Errami, Y; Zerfaoui, M; Kim, H; Kim, JG; Abd Elmageed, ZY; Abdel-Mageed, AB; Giardina, C; Beg, AA; Smulson, ME; Boulares, AH,期刊:Journal of Biological Chemistry, 页码:U161-U168 , 文章类型: Article,,卷期:2010年285-52]
- The DNA binding activity of NF-kappa B is critical for VCAM-1 expression during inflammation. DNA-dependent protein kinase (DNA-PK) is thought to be involved in NF-kappa B activation. Here we show that DNA-PK is required...
- The 1.5 angstrom Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE) Ectodomains Reveals Unique Features Determining Ligand Binding
[作者:Park, H; Boyington, JC,期刊:Journal of Biological Chemistry, 页码:U161-U168 , 文章类型: Article,,卷期:2010年285-52]
- Interaction of the pattern recognition receptor, RAGE with key ligands such as advanced glycation end products (AGE), S100 proteins, amyloid beta, and HMGB1 has been linked to diabetic complications, inflammatory and neu...
- Assessment of the Validity of the Double Superhelix Model for Reconstituted High Density Lipoproteins A COMBINED COMPUTATIONAL-EXPERIMENTAL APPROACH
[作者:Jones, MK; Zhang, L; Catte, A; Li, L; Oda, MN; Ren, G; Segrest, JP,期刊:Journal of Biological Chemistry, 页码:U161-U168 , 文章类型: Article,,卷期:2010年285-52]
- For several decades, the standard model for high density lipoprotein (HDL) particles reconstituted from apolipoprotein A-I (apoA-I) and phospholipid (apoA-I/HDL) has been a discoidal particle similar to 100 angstrom in d...
- Transgenic Mice with -6A Haplotype of the Human Angiotensinogen Gene Have Increased Blood Pressure Compared with -6G Haplotype
[作者:Jain, S; Tillinger, A; Mopidevi, B; Pandey, VG; Chauhan, CK; Fiering, SN; Warming, S; Kumar, A,期刊:Journal of Biological Chemistry, 页码:U161-U168 , 文章类型: Article,,卷期:2010年285-52]
- Hypertension is a serious risk factor for cardiovascular disease, and the angiotensinogen (AGT) gene locus is associated with human essential hypertension. The human AGT (hAGT) gene has an A/G polymorphism at -6, and the...
- Response to Aliev et al.: PCr and ATP Export Both Participate in Energy Transfer from Mitochondria in Normoxic Heart
[作者:Vendelin, M; Mateo, P; Soboll, S; Gillet, B; Mazet, JL; Hoerter, JA,期刊:Journal of Biological Chemistry, 页码:889-898 , 文章类型: Letter,,卷期:2010年285-52]
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