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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共17条记录   Benzofuran Derivatives as Potent, Orally Active S1P(1) Receptor Agonists: A Preclinical Lead Molecule for MS [作者：SAHA ASHIS K; YU XIANG; LIN JIAN; LOBERA MERCEDES; SHARADENDU ANURAG; CHEREKU SRINIVAS; SCHUTZ NILI; SEGAL DALIA; MARANTZ YAEL; MCCAULEY DILARA; MIDDLETON SCOT; SIU JERRY; BUERLI ROLAND W; BUYS JANET; HORNER MICHELLE; SALYERIS KEVIN; SCHRAG MICHAEL; VARGAS HUGO M; XU YANG; MCELVAIN MICHELE; XU HAN,期刊：ACS Medicinal Chemistry Letters, 页码：97-101 , 文章类型： Article，,卷期：2011年2-2] We have discovered novel benzofuran-based S1P(1) agonists with excellent in vitro potency and selectivity. 1-((4-(5-Benzylbenzofuran-2-yl)-3-fluorophenyl)methyl) azetidine-3-carboxylic acid (18) is a potent S1P(1) agonis...