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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共24条记录   CD and MCD Spectroscopic Studies of the Two Dps Miniferritin Proteins from Bacillus anthracis: Role of O-2 and H2O2 Substrates in Reactivity of the Diiron Catalytic Centers [作者：Schwartz, JK; Liu, XFS; Tosha, T; Diebold, A; Theil, EC; Solomon, EI,期刊：Biochemistry, 页码：10516-10525 , 文章类型： Article，,卷期：2010年49-49] DNA protection during starvation (Dps) proteins are miniferritins found in bacteria and archaea that provide protection from uncontrolled Fe(II)/O radical chemistry; thus the catalytic sites are targets for antibiotics a... Cross-Talk between the Catalytic Core and the Regulatory Domain in Cystathionine beta-Synthase: Study by Differential Covalent Labeling and Computational Modeling [作者：Hnizda, A; Spiwok, V; Jurga, V; Kozich, V; Kodicek, M; Kraus, JP,期刊：Biochemistry, 页码：10526-10534 , 文章类型： Article，,卷期：2010年49-49] Cystathionine beta-synthase (CBS) is a modular enzyme which catalyzes condensation of serine with homocysteine. Cross-talk between the catalytic core and the C-terminal regulatory domain modulates the enzyme activity. Th... Characterization of Kinetic and Thermodynamic Phases in the Prefolding Process of Bovine Pancreatic Ribonuclease A Coupled with Fast SS Formation and SS Reshuffling [作者：Arai, K; Kumakura, F; Iwaoka, M,期刊：Biochemistry, 页码：10535-10542 , 文章类型： Article，,卷期：2010年49-49] In the redox-coupled oxidative folding of a protein having several SS bonds, two folding phases are usually observed, corresponding to SS formation (oxidation) with generation of weakly stabilized heterogeneous structure... DNA Binding Characteristics of Mithramycin and Chromomycin Analogues Obtained by Combinatorial Biosynthesis [作者：Barcelo, F; Ortiz-Lombardia, M; Martorell, M; Oliver, M; Mendez, C; Salas, JA; Portugal, J,期刊：Biochemistry, 页码：10543-10552 , 文章类型： Article，,卷期：2010年49-49] The antitumor antibiotics mithramycin A and chromomycin A(3) bind reversibly to the minor groove of G/C-rich regions in DNA in the presence of dications such as Mg2+, and their antiproliferative activity has been associa... Molecular Level Insights into Thermally Induced alpha-Chymotrypsinogen A Amyloid Aggregation Mechanism and Semiflexible Protofibril Morphology [作者：Zhang, A; Jordan, JL; Ivanova, MI; Weiss, WF; Roberts, CJ; Fernandez, EJ,期刊：Biochemistry, 页码：10553-10564 , 文章类型： Article，,卷期：2010年49-49] Understanding nonnative protein aggregation is critical not only to a number of amyloidosis disorders but also for the development of effective and safe biopharmaceuticals. In a series of previous studies [Weiss et al. (... Efavirenz Binding Site in HIV-1 Reverse Transcriptase Monomers [作者：Braz, VA; Barkley, MD; Jockusch, RA; Wintrode, PL,期刊：Biochemistry, 页码：10565-10573 , 文章类型： Article，,卷期：2010年49-49] Efavirenz (EFV) is a potent nonnucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of AIDS. NNRTIs bind in a hydrophobic pocket located in the p66 subunit of reverse transcriptase (RT), which is not ... Consecutive Terminal GU Pairs Stabilize RNA Helices [作者：Nguyen, MT; Schroeder, SJ,期刊：Biochemistry, 页码：10574-10581 , 文章类型： Article，,卷期：2010年49-49] Consecutive GU pairs at the ends of RNA helices provide significant thermodynamic stability between -1.0 and -3.8 kcal/mol at 37 degrees C, which is equivalent to approximately 2 orders of magnitude in the value of a bin... The Second-Shell Metal Ligands of Human Arginase Affect Coordination of the Nucleophile and Substrate [作者：Stone, EM; Chantranupong, L; Georgiou, G,期刊：Biochemistry, 页码：10582-10588 , 文章类型： Article，,卷期：2010年49-49] The active sites of eukaryotic arginase enzymes are strictly conserved, especially the first- and second-shell ligands that coordinate the two divalent metal cations that generate a hydroxide molecule for nucleophilic at...