- Assessment of Tumor Development and Wound Healing Using Endoscopic Techniques in Mice
[作者:Neurath, MF; Wittkopf, N; Wlodarski, A; Waldner, M; Neufert, C; Wirtz, S; Gunther, C; Becker, C,期刊:Gastroenterology, 页码:1837-U93 , 文章类型: Article,,卷期:2010年139-6]
- Mouse models of intestinal inflammation and colon cancer are valuable tools to gain insights into the pathogenesis of the corresponding human diseases. Recently, in vivo mouse endoscopy has been developed, allowing not o...
- Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice
[作者:Bercik, P; Verdu, EF; Foster, JA; Macri, J; Potter, M; Huang, XX; Malinowski, P; Jackson, W; Blennerhassett, P; Neufeld, KA; Lu, J; Khan, WI; Corthesy-Theulaz, I; Cherbut, C; Bergonzelli, GE; Collins, SM,期刊:Gastroenterology, 页码:2102-U409 , 文章类型: Article,,卷期:2010年139-6]
- BACKGROUND & AIMS: Clinical and preclinical studies have associated gastrointestinal inflammation and infection with altered behavior. We investigated whether chronic gut inflammation alters behavior and brain biochemist...
- NOTCH1 and NOTCH3 Coordinate Esophageal Squamous Differentiation Through a CSL-Dependent Transcriptional Network
[作者:Ohashi, S; Natsuizaka, M; Yashiro-Ohtani, Y; Kalman, RA; Nakagawa, M; Wu, LZ; Klein-Szanto, AJ; Herlyn, M; Diehl, JA; Katz, JP; Pear, WS; Seykora, JT; Nakagawa, H,期刊:Gastroenterology, 页码:2113-2123 , 文章类型: Article,,卷期:2010年139-6]
- BACKGROUND & AIMS: The Notch receptor family regulates cell fate through cell-cell communication. CSL (CBF-1/RBP-j kappa, Su(H), Lag-1) drives canonical Notch-mediated gene transcription during cell lineage specification...
- KLF4 alpha Up-regulation Promotes Cell Cycle Progression and Reduces Survival Time of Patients With Pancreatic Cancer
[作者:Wei, DY; Wang, LW; Kanai, M; Jia, ZL; Le, XD; Li, QA; Wang, HM; Xie, KP,期刊:Gastroenterology, 页码:2135-2145 , 文章类型: Article,,卷期:2010年139-6]
- BACKGROUND & AIMS: Kruppel-like factor 4 (KLF4) is a transcription factor associated with tumor suppression and oncogenesis. KLF4 suppresses pancreatic tumorigenesis by unknown mechanisms; we investigated alterations tha...
- Up-regulation of Kruppel-Like Factor 8 Promotes Tumor Invasion and Indicates Poor Prognosis for Hepatocellular Carcinoma
[作者:Li, JC; Yang, XR; Sun, HX; Xu, Y; Zhou, JA; Qiu, SJ; Ke, AW; Cui, YH; Wang, ZJ; Wang, WM; Liu, KD; Fan, J,期刊:Gastroenterology, 页码:2146-U475 , 文章类型: Article,,卷期:2010年139-6]
- BACKGROUND & AIMS: The transcription factor Kruppel-like factor 8 (KLF8) has a role in tumor development, growth, and metastasis, but its role in hepatocellular carcinoma (HCC) is not clear. METHODS: KLF8 expression in h...
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