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  • Total Syntheses of Tubulysins
    [作者:SHIBUE TAKU; HIRAI TOSHIHIRO; OKAMOTO IWAO; MORITA NOBUYOSHI; MASU HYUMA; AZUMAYA ISAO; TAMURA OSAMU,期刊:Chemistry-A European Journal, 页码:11678-11688 , 文章类型: Article,,卷期:2010年16-38]
  • The total syntheses of tetrapeptides tubulysins D (1b), U (1 c), and V (1d), which are potent tubulin polymerization inhibitors, are described. The synthesis of Tuv (2), an unusual amino acid constituent of tubulysins, i...